[Lateral hypothalamus stimulation as a conditioned stimulus for an alimentary instrumental reflex]. 1978

O G Pavlova

Dynamics of the behavioral effects of LH-stimulation which was used as a conditioned stimulus of alimentary reflex, was recorded in dogs during reflex elaboration, extinction and restoration. Before the elaboration, LH-stimulation elicited either an alimentary instrumental relflex, previously established, or a searching, sniffing, licking, orienting reaction, in the majority of cases with variable latencies. Combination of stimulation and achievement of the alimentary instrumental reflex with subsequent reinforcement in short time stabilized the feeding response. Searching, sniffing, orienting reaction disappeared during the elaboration of the conditioned reflex. Elimination of food reinforcement led to extinction of the alimentary reflex to LH-stimulation. In some sessions full abolition of the feeding response was achieved. LH-stimulation inhibitory properties are assumed. The restoration of the alimentary response to LH-stimulation after single reinforcement demonstrated a high plasticity of this structure. The dynamics of the reflex elaboration, extinction and restoration was the same in response both to brain stimulation and to distant stimuli (sound and light). The implicit motivational properties of LH-stimulation were manifested in the ability to activate the feeding behavior in the satiated dogs.

UI MeSH Term Description Entries
D007031 Hypothalamus Ventral part of the DIENCEPHALON extending from the region of the OPTIC CHIASM to the caudal border of the MAMMILLARY BODIES and forming the inferior and lateral walls of the THIRD VENTRICLE. Lamina Terminalis,Preoptico-Hypothalamic Area,Area, Preoptico-Hypothalamic,Areas, Preoptico-Hypothalamic,Preoptico Hypothalamic Area,Preoptico-Hypothalamic Areas
D008027 Light That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range. Light, Visible,Photoradiation,Radiation, Visible,Visible Radiation,Photoradiations,Radiations, Visible,Visible Light,Visible Radiations
D011930 Reaction Time The time from the onset of a stimulus until a response is observed. Response Latency,Response Speed,Response Time,Latency, Response,Reaction Times,Response Latencies,Response Times,Speed, Response,Speeds, Response
D003216 Conditioning, Operant Learning situations in which the sequence responses of the subject are instrumental in producing reinforcement. When the correct response occurs, which involves the selection from among a repertoire of responses, the subject is immediately reinforced. Instrumental Learning,Learning, Instrumental,Operant Conditioning,Conditionings, Operant,Instrumental Learnings,Learnings, Instrumental,Operant Conditionings
D003463 Cues Signals for an action; that specific portion of a perceptual field or pattern of stimuli to which a subject has learned to respond. Cue
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D004558 Electric Stimulation Use of electric potential or currents to elicit biological responses. Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical
D005108 Extinction, Psychological The procedure of presenting the conditioned stimulus without REINFORCEMENT to an organism previously conditioned. It refers also to the diminution of a conditioned response resulting from this procedure. Psychological Extinction,Extinction (Psychology),Extinctions (Psychology),Extinctions, Psychological,Psychological Extinctions
D005502 Food Substances taken in by the body to provide nourishment. Foods
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

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