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Thirty consecutive patients with thyrotoxicosis were followed up at monthly intervals for 6 months after treatment with iodine-131. Serum total T4, serum total T3, and serum TSH response to TRH were measured at each review. Biochemical evidence of hypothyroidism (low T4 raised basal TSH) developed in 18 patients 1-4 months after treatment. In 5 of these patients, symptoms and signs of hypothyroidism remained absent or minimal and spontaneous recovery of thyroid function occurred during the ensuing 2 months. If biochemical hypothyroidism occurs during the first 6 months after radioiodine therapy, it is recommended that T4 replacement be withheld for 2 months unless the severity of symptoms demands treatment.
J S Sawers, and
A D Toft, and
W J Irvine, and
N S Brown, and
J Seth
August 1979,
British medical journal,
J S Sawers, and
A D Toft, and
W J Irvine, and
N S Brown, and
J Seth
December 1989,
Thyroidology,
J S Sawers, and
A D Toft, and
W J Irvine, and
N S Brown, and
J Seth
July 1971,
Annals of internal medicine,
J S Sawers, and
A D Toft, and
W J Irvine, and
N S Brown, and
J Seth
April 1998,
Clinical endocrinology,
J S Sawers, and
A D Toft, and
W J Irvine, and
N S Brown, and
J Seth
September 1995,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
J S Sawers, and
A D Toft, and
W J Irvine, and
N S Brown, and
J Seth
January 1984,
Clinical nuclear medicine,
J S Sawers, and
A D Toft, and
W J Irvine, and
N S Brown, and
J Seth
December 1983,
The Medical journal of Malaysia,
J S Sawers, and
A D Toft, and
W J Irvine, and
N S Brown, and
J Seth
April 1964,
British medical journal,
J S Sawers, and
A D Toft, and
W J Irvine, and
N S Brown, and
J Seth
January 1973,
Problemes actuels d'endocrinologie et de nutrition,
J S Sawers, and
A D Toft, and
W J Irvine, and
N S Brown, and
J Seth
October 1978,
British medical journal,
