Biomaterial Database

Stapedius reflex quantification in acoustic tumor patients. 1980

C A Mangham, and R C Lindeman, and W R Dawson

This investigation is a human application of previously reported work from our laboratories on experimental acoustic tumor effects on the stapedius reflex in monkeys. In this study, the contralateral stapedius reflex was elicited in human controls and in subjects with an acoustic tumor. Acoustic impedance was recorded on magnetic tape for offline analysis of reflex threshold, latency, rise, amplitude, decay, and relaxation. Typical tumor effects on threshold and decay were observed. Most important was the demonstration that decay measured at 20 db SL was more sensitive and more specific for tumor than decay measured at the conventional 10 db SL. Stapedius reflex latency, rise, and amplitude were more sensitive to the presence of a tumor than were measures of threshold and decay. These data indicate that qualification of the reflex will increase the utility of the test.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009132	Muscles	Contractile tissue that produces movement in animals.	Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D012018	Reflex	An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.
D003390	Cranial Nerve Neoplasms	Benign and malignant neoplasms that arise from one or more of the twelve cranial nerves.	Cranial Neuroma, Benign,Benign Cranial Nerve Neoplasms,Benign Cranial Nerve Tumors,Cranial Nerve Neoplasms, Benign,Cranial Nerve Neoplasms, Malignant,Cranial Nerve Tumors, Benign,Cranial Nerve Tumors, Malignant,Malignant Cranial Nerve Neoplasms,Malignant Cranial Nerve Tumors,Neoplasms, Cranial Nerve,Neoplasms, Cranial Nerve, Benign,Neoplasms, Cranial Nerve, Malignant,Tumors, Cranial Nerve, Benign,Tumors, Cranial Nerve, Malignant,Benign Cranial Neuroma,Benign Cranial Neuromas,Cranial Nerve Neoplasm,Cranial Neuromas, Benign,Neoplasm, Cranial Nerve,Neuroma, Benign Cranial,Neuromas, Benign Cranial
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000158	Acoustic Impedance Tests	Objective tests of middle ear function based on the difficulty (impedance) or ease (admittance) of sound flow through the middle ear. These include static impedance and dynamic impedance (i.e., tympanometry and impedance tests in conjunction with intra-aural muscle reflex elicitation). This term is used also for various components of impedance and admittance (e.g., compliance, conductance, reactance, resistance, susceptance).	Audiometry, Impedance,Electroacoustic Impedance Tests,Impedance Tests, Acoustic,Tympanometry,Acoustic Impedance Test,Electroacoustic Impedance Test,Impedance Audiometry,Impedance Test, Acoustic,Impedance Test, Electroacoustic,Impedance Tests, Electroacoustic,Test, Acoustic Impedance,Test, Electroacoustic Impedance,Tests, Acoustic Impedance,Tests, Electroacoustic Impedance
D000160	Vestibulocochlear Nerve Diseases	Pathological processes of the VESTIBULOCOCHLEAR NERVE, including the branches of COCHLEAR NERVE and VESTIBULAR NERVE. Common examples are VESTIBULAR NEURITIS, cochlear neuritis, and ACOUSTIC NEUROMA. Clinical signs are varying degree of HEARING LOSS; VERTIGO; and TINNITUS.	Acoustic Nerve Diseases,Cochlear Nerve Diseases,Cranial Nerve VIII Diseases,Vestibular Nerve Diseases,Acoustic Nerve Disorders,Cochlear Nerve Disorders,Cochlear Neuritis,Cranial Nerve VIII Disorders,Eighth Cranial Nerve Diseases,Vestibular Nerve Disorders,Acoustic Nerve Disease,Acoustic Nerve Disorder,Cochlear Nerve Disease,Cochlear Nerve Disorder,Cochlear Neuritides,Neuritides, Cochlear,Neuritis, Cochlear,Vestibular Nerve Disease,Vestibular Nerve Disorder,Vestibulocochlear Nerve Disease
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults