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An abnormal hemoglobin with increased oxygen affinity has to be suspected in all the cases of polycythemia where no direct signs of "polycythemia vera", or any of the classical reasons for erythropoietic stimulation can be demonstrated. This fact is documented by two new observations, one concerning a 44 year-old man with Hb Kempsey, another concerning a 58 year-old woman with Hb Malmö. The diagnosis is based on a scrupulous electrophoretic study involving an isoelectric focusing on polyacrylamide gel, and, on the study of the oxygen binding properties of the red blood cells. This polycythemia being a compensatory mechanism allowing a normal oxygen delivery to the tissues has to be respected and a compromise must be found with the cardiovascular risk.
G Gacon, and
H Wajcman, and
O Belkhodja-Dunda, and
D Labie, and
J Bousser
February 2002,
Clinical chemistry,
G Gacon, and
H Wajcman, and
O Belkhodja-Dunda, and
D Labie, and
J Bousser
March 1969,
The New England journal of medicine,
G Gacon, and
H Wajcman, and
O Belkhodja-Dunda, and
D Labie, and
J Bousser
March 1974,
Casopis lekaru ceskych,
G Gacon, and
H Wajcman, and
O Belkhodja-Dunda, and
D Labie, and
J Bousser
January 1974,
Pneumonologie. Pneumonology,
G Gacon, and
H Wajcman, and
O Belkhodja-Dunda, and
D Labie, and
J Bousser
January 1980,
Respiration; international review of thoracic diseases,
G Gacon, and
H Wajcman, and
O Belkhodja-Dunda, and
D Labie, and
J Bousser
January 1980,
Bibliotheca haematologica,
G Gacon, and
H Wajcman, and
O Belkhodja-Dunda, and
D Labie, and
J Bousser
March 1974,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
G Gacon, and
H Wajcman, and
O Belkhodja-Dunda, and
D Labie, and
J Bousser
February 1980,
Zeitschrift fur Geburtshilfe und Perinatologie,
G Gacon, and
H Wajcman, and
O Belkhodja-Dunda, and
D Labie, and
J Bousser
January 1980,
Bibliotheca haematologica,
G Gacon, and
H Wajcman, and
O Belkhodja-Dunda, and
D Labie, and
J Bousser
January 1989,
Advances in experimental medicine and biology,
