High-performance liquid chromatographic micro-assay for chloramphenicol in human blood plasma and cerebrospinal fluid.
1980
J Gal, and
P D Marcell, and
C M Tarascio
UI
MeSH Term
Description
Entries
D002701
Chloramphenicol
An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)