BIOMAT Database Logo BIOMAT Database Logo

Cloacal gland of the Japanese quail: androgen dependence and metabolism of testosterone. 1980

R Massa, and D T Davies, and L Bottoni

A cloacal gland complex whose growth and development is androgen-dependent exists in the Japanese quail. In-vitro incubation studies of the cloacal gland using 4-14C-labelled testosterone as substrate allowed the positive identification of five metabolites: androstenedione, 5 beta-dihydrotestosterone (5 beta-DHT), 5 beta-androstane-3 alpha, 17 beta-diol, 5 alpha-DHT and 5 alpha -androstane-3 alpha, 17 beta-diol. More polar metabolites, not yet chemically identified, were detected in trace amounts. Androstenedione appeared to be the main testosterone metabolite in immature birds while in mature birds on long daylengths testosterone was preferentially metabolized to 5 alpha-DHT. This change may have been in response to the higher levels of plasma steroids found in mature birds. When various testosterone metabolites, contained in silicone elastomer capsules, were implanted s.c. into castrated birds maintained on a photostimulatory light regime, 5 alpha-DHT, 5 alpha-androstane-3,17-dione, androstenedione and 5 alpha-androstan-3 alpha-ol-17-one were shown to be equipotent with testosterone in stimulating the development of the cloacal gland. 5 alpha-Androstane-3 alpha, 17 beta-diol and 5 alpha-androstan-3 beta-ol-17-one stimulated some growth while 5 beta-DHT, 5 alpha-androstane-3 beta, 17 beta-diol, 5 alpha-androstane-3 alpha, 17 beta-diol, 5 beta-androstane-3,17-dione, androst-5-en-3 beta-ol-17-one and androst-5-ene-3 beta, 17 beta-diol were completely ineffective.

UI MeSH Term Description Entries
D008027 Light That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range. Light, Visible,Photoradiation,Radiation, Visible,Visible Radiation,Photoradiations,Radiations, Visible,Visible Light,Visible Radiations
D008297 Male Males
D011784 Quail Common name for two distinct groups of BIRDS in the order GALLIFORMES: the New World or American quails of the family Odontophoridae and the Old World quails in the genus COTURNIX, family Phasianidae. Quails
D002369 Castration Surgical removal or artificial destruction of gonads. Gonadectomy,Castrations,Gonadectomies
D002988 Cloaca A dilated cavity extended caudally from the hindgut. In adult birds, reptiles, amphibians, and many fishes but few mammals, cloaca is a common chamber into which the digestive, urinary and reproductive tracts discharge their contents. In most mammals, cloaca gives rise to LARGE INTESTINE; URINARY BLADDER; and GENITALIA. Cloacas
D003370 Coturnix A genus of BIRDS in the family Phasianidae, order GALLIFORMES, containing the common European and other Old World QUAIL. Japanese Quail,Coturnix japonica,Japanese Quails,Quail, Japanese,Quails, Japanese
D000728 Androgens Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power. Androgen,Androgen Receptor Agonist,Androgen Effect,Androgen Effects,Androgen Receptor Agonists,Androgenic Agents,Androgenic Compounds,Agents, Androgenic,Agonist, Androgen Receptor,Agonists, Androgen Receptor,Compounds, Androgenic,Effect, Androgen,Effects, Androgen,Receptor Agonist, Androgen,Receptor Agonists, Androgen
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012741 Sexual Maturation Achievement of full sexual capacity in animals and in humans. Sex Maturation,Maturation, Sex,Maturation, Sexual
D013196 Dihydrotestosterone A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE. 5 alpha-Dihydrotestosterone,Androstanolone,Stanolone,17 beta-Hydroxy-5 beta-Androstan-3-One,17beta-Hydroxy-5alpha-Androstan-3-One,5 beta-Dihydrotestosterone,5-alpha Dihydrotestosterone,5-alpha-DHT,Anaprotin,Andractim,Dihydroepitestosterone,Gelovit,17 beta Hydroxy 5 beta Androstan 3 One,17beta Hydroxy 5alpha Androstan 3 One,5 alpha DHT,5 alpha Dihydrotestosterone,5 beta Dihydrotestosterone,Dihydrotestosterone, 5-alpha,beta-Hydroxy-5 beta-Androstan-3-One, 17

Related Publications

R Massa, and D T Davies, and L Bottoni
Photoperiodic control of testosterone metabolism, plasma gonadotrophins, cloacal gland growth, and reproductive behavior in the Japanese quail.
October 1979, General and comparative endocrinology,
R Massa, and D T Davies, and L Bottoni
The cloacal gland complex of the Japanese quail.
September 1968, Experientia,
R Massa, and D T Davies, and L Bottoni
Changes in testosterone metabolism by the brain and cloacal gland during sexual maturation in the Japanese quail (Coturnix coturnix japonica).
January 1984, The Journal of endocrinology,
R Massa, and D T Davies, and L Bottoni
Photoperiodic control of the cloacal gland of the Japanese quail.
July 1967, Science (New York, N.Y.),
R Massa, and D T Davies, and L Bottoni
Relationship of cloacal gland with testes, testosterone and fertility in different lines of male Japanese quail.
January 2007, Animal reproduction science,
R Massa, and D T Davies, and L Bottoni
Inhibition of testosterone metabolism in the brain and cloacal gland of the quail by specific inhibitors and antihormones.
February 1987, The Journal of endocrinology,
R Massa, and D T Davies, and L Bottoni
Testosterone metabolism and testosterone-dependent characteristics in Japanese quail.
November 1984, Physiology & behavior,
R Massa, and D T Davies, and L Bottoni
Residues of fluoroquinolone drugs in the cloacal gland and other tissues of Japanese quail.
February 2006, British poultry science,
R Massa, and D T Davies, and L Bottoni
Relative potencies of testosterone and 5 alpha-dihydrotestosterone on crowing and cloacal gland growth in the Japanese quail (Coturnix coturnix japonica).
January 1984, The Journal of endocrinology,
R Massa, and D T Davies, and L Bottoni
Testosterone metabolism in the uropygial gland of the quail.
May 1985, Steroids,
Copied contents to your clipboard!