Ochratoxin A as the cause of spontaneous nephropathy in fattening pigs. 1978

L Rutqvist, and N E Björklund, and K Hult, and E Hökby, and B Carlsson

At a number of slaughters nephropathy and high ochratoxin A contents in kidneys have been observed in fattening pigs from two Swedish farms. In one herd the source of contamination was barley grown on the home farm and stored under such conditions that the growth of fungal species (Penicillium verrucosum var. verrucosum) producing ochratoxin A occurred, with the subsequent formation of the toxin. In this case high ochratoxin A levels in fattening pigs were found during a period of about 18 months. In the second herd, where compounded feed was used, it was impossible to locate the source of contamination. It was presumed that a consignment of feed was damaged by rain during storage at the farm. Ochratoxin A was found in fattening pigs from this herd for a period of about 2 months. Ochratoxin A appeared in the kidneys of all investigated pigs. In some animals the livers, whole blood, and plasma were analyzed, too. The livers contained somewhat lower amounts of ochratoxin A than the kidneys, whereas the content in whole blood and plasma, respectively, was 5 and 13 times greater. Kidneys spontaneously contaminated with ochratoxin A, when stored for 10 months at -70 degrees C, showed no systematic decrease in toxin content.

UI MeSH Term Description Entries
D007668 Kidney Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. Kidneys
D007674 Kidney Diseases Pathological processes of the KIDNEY or its component tissues. Disease, Kidney,Diseases, Kidney,Kidney Disease
D009793 Ochratoxins Isocoumarins found in ASPERGILLUS OCHRACEUS and other FUNGI. Ochratoxin contaminated FOOD has been responsible for cases of FOODBORNE DISEASES. Ochratoxin
D010407 Penicillium A mitosporic Trichocomaceae fungal genus that develops fruiting organs resembling a broom. When identified, teleomorphs include EUPENICILLIUM and TALAROMYCES. Several species (but especially PENICILLIUM CHRYSOGENUM) are sources of the antibiotic penicillin. Penicilliums
D005516 Food Microbiology The presence of bacteria, viruses, and fungi in food and food products. This term is not restricted to pathogenic organisms: the presence of various non-pathogenic bacteria and fungi in cheeses and wines, for example, is included in this concept. Microbiology, Food
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000821 Animal Feed Foodstuff used especially for domestic and laboratory animals, or livestock. Fodder,Animal Feeds,Feed, Animal,Feeds, Animal,Fodders
D001467 Hordeum A plant genus of the family POACEAE. The EDIBLE GRAIN, barley, is widely used as food. Barley,Hordeum vulgare
D013552 Swine Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA). Phacochoerus,Pigs,Suidae,Warthogs,Wart Hogs,Hog, Wart,Hogs, Wart,Wart Hog
D013553 Swine Diseases Diseases of domestic swine and of the wild boar of the genus Sus. Disease, Swine,Diseases, Swine,Swine Disease

Related Publications

L Rutqvist, and N E Björklund, and K Hult, and E Hökby, and B Carlsson
September 1977, Nordisk veterinaermedicin,
L Rutqvist, and N E Björklund, and K Hult, and E Hökby, and B Carlsson
November 1975, Acta pathologica et microbiologica Scandinavica. Section A, Pathology,
L Rutqvist, and N E Björklund, and K Hult, and E Hökby, and B Carlsson
January 1995, Archiv fur Tierernahrung,
L Rutqvist, and N E Björklund, and K Hult, and E Hökby, and B Carlsson
December 1998, Veterinary and human toxicology,
L Rutqvist, and N E Björklund, and K Hult, and E Hökby, and B Carlsson
March 1990, The Veterinary record,
L Rutqvist, and N E Björklund, and K Hult, and E Hökby, and B Carlsson
November 2008, International journal of molecular sciences,
L Rutqvist, and N E Björklund, and K Hult, and E Hökby, and B Carlsson
April 2001, Veterinary research communications,
L Rutqvist, and N E Björklund, and K Hult, and E Hökby, and B Carlsson
October 1981, The Veterinary record,
L Rutqvist, and N E Björklund, and K Hult, and E Hökby, and B Carlsson
September 1978, Schweizer Archiv fur Tierheilkunde,
L Rutqvist, and N E Björklund, and K Hult, and E Hökby, and B Carlsson
January 1986, Developments in toxicology and environmental science,
Copied contents to your clipboard!