BIOMAT Database Logo BIOMAT Database Logo

[Electron microscopic investigation on cutaneous leiomyosarcoma (author's transl)]. 1978

H W Seifert

A 61-year old woman developed a tumourous nodule in her left leg. Fifteen years ago a similar tumour had been removed in the same localization. Histological examination performed on biopsy material showed bundles of predominantly fusiform tumour cells with nuclear pleomorphism and many mitotic figures. Electron microscopic examination confirmed the diagnosis of leiomyosarcoma by demonstration of the ultrastructural characteristics of smooth muscle cells. Cellular differentiation showed various degree ranging from smooth muscle cell type to dedifferentiated edematous tumour cells with scanty myofilaments. An important finding was the demonstration of multiple accumulated centrioles.

UI MeSH Term Description Entries
D007866 Leg The inferior part of the lower extremity between the KNEE and the ANKLE. Legs
D007890 Leiomyosarcoma A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865) Leiomyosarcoma, Epithelioid,Leiomyosarcoma, Myxoid,Epithelioid Leiomyosarcoma,Epithelioid Leiomyosarcomas,Leiomyosarcomas,Leiomyosarcomas, Epithelioid,Leiomyosarcomas, Myxoid,Myxoid Leiomyosarcoma,Myxoid Leiomyosarcomas
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009364 Neoplasm Recurrence, Local The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site. Local Neoplasm Recurrence,Local Neoplasm Recurrences,Locoregional Neoplasm Recurrence,Neoplasm Recurrence, Locoregional,Neoplasm Recurrences, Local,Recurrence, Local Neoplasm,Recurrence, Locoregional Neoplasm,Recurrences, Local Neoplasm,Locoregional Neoplasm Recurrences,Neoplasm Recurrences, Locoregional,Recurrences, Locoregional Neoplasm
D002454 Cell Differentiation Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs. Differentiation, Cell,Cell Differentiations,Differentiations, Cell
D002502 Centrioles Self-replicating, short, fibrous, rod-shaped organelles. Each centriole is a short cylinder containing nine pairs of peripheral microtubules, arranged so as to form the wall of the cylinder. Centriole
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012867 Skin The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.

Related Publications

H W Seifert
[Phagocytosis of lymphocytes. Electron microscopic investigation (author's transl)].
June 1974, Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie,
H W Seifert
[Scanning electron-microscopic investigation of human tendons (author's transl)].
January 1982, Magyar traumatologia, orthopaedia es helyreallito sebeszet,
H W Seifert
[Electron microscopic investigation on the postnatal growth of myocardial cells (author's transl)].
January 1971, Verhandlungen der Deutschen Gesellschaft fur Pathologie,
H W Seifert
[Embedding of undecalcified bone tissue for electron microscopic investigation (author's transl)].
December 1975, Beitrage zur Pathologie,
H W Seifert
[Electron microscopic studies on retinal dysplasia (author's transl)].
May 1975, Nippon Ganka Gakkai zasshi,
H W Seifert
[Electron microscopic study on laryngeal cancer (author's transl)].
August 1976, Nihon Jibiinkoka Gakkai kaiho,
H W Seifert
[Electron microscopic autoradiography on semithin sections (author's transl)].
January 1979, Acta histochemica,
H W Seifert
[Electron microscopic investigations on encapsulated Staphylococci (author's transl)].
March 1976, Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie,
H W Seifert
[Thalassemia minor, electron microscopic (author's transl)].
January 1981, Bratislavske lekarske listy,
H W Seifert
[Electron-microscopic observations on platelet aggregation groups (author's transl)].
September 1981, Zhonghua yi xue za zhi,
Copied contents to your clipboard!