Biomaterial Database

[Hepatosplenic disorders in schistosomiasis (author's transl)]. 1980

P Aubry, and P Capdevielle, and G Durand

Hepatosplenic disorders start in the invasion stage and are from immuno-allergic origin. Then, they develop during the ovular laying stage; hepatic disorders are due to periovular granulomatosis, and splenic disorders are due to reticulo-endothelial system reaction. Their last aspect is the portal fibrosis, called Symmer's "clay pipe", in which HTP is consequent to hepatic disorder and the main cause of splenomegaly. The location of S. japonicum and S. mansoni in pericolic veins explains that hepatic ovular deposits are much more frequent than with S. haematobium that is located in bladder veins. S. intercalatum, living in perirectal veins, may also disseminate some eggs in the liver. HTP most often requires surgical intervention. The diagnostic approach of hepatosplenic disorders in schistosomiasis is described and discussed.

UI	MeSH Term	Description	Entries
D006975	Hypertension, Portal	Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.	Cruveilhier-Baumgarten Disease,Cruveilhier-Baumgarten Syndrome,Cruveilhier Baumgarten Disease,Cruveilhier Baumgarten Syndrome,Disease, Cruveilhier-Baumgarten,Portal Hypertension,Portal Hypertensions,Syndrome, Cruveilhier-Baumgarten
D008109	Liver Diseases, Parasitic	Liver diseases caused by infections with PARASITES, such as tapeworms (CESTODA) and flukes (TREMATODA).	Parasitic Liver Diseases,Disease, Parasitic Liver,Diseases, Parasitic Liver,Liver Disease, Parasitic,Parasitic Liver Disease
D006099	Granuloma	A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.	Granulomas
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012548	Schistosoma haematobium	A species of trematode blood flukes of the family Schistosomatidae which occurs at different stages in development in veins of the pulmonary and hepatic system and finally the bladder lumen. This parasite causes urinary schistosomiasis.	Schistosoma haematobiums,haematobiums, Schistosoma
D012549	Schistosoma japonicum	A species of trematode blood flukes belonging to the family Schistosomatidae whose distribution is confined to areas of the ASIA, EASTERN. The intermediate host is a snail. It occurs in man and other mammals.	Schistosoma japonicums,japonicum, Schistosoma
D012550	Schistosoma mansoni	A species of trematode blood flukes of the family Schistosomatidae. It is common in the Nile delta. The intermediate host is the planorbid snail. This parasite causes schistosomiasis mansoni and intestinal bilharziasis.	Schistosoma mansonus,mansonus, Schistosoma
D012552	Schistosomiasis	Infection with flukes (trematodes) of the genus SCHISTOSOMA. Three species produce the most frequent clinical diseases: SCHISTOSOMA HAEMATOBIUM (endemic in Africa and the Middle East), SCHISTOSOMA MANSONI (in Egypt, northern and southern Africa, some West Indies islands, northern 2/3 of South America), and SCHISTOSOMA JAPONICUM (in Japan, China, the Philippines, Celebes, Thailand, Laos). S. mansoni is often seen in Puerto Ricans living in the United States.	Bilharziasis,Katayama Fever,Schistoma Infection,Bilharziases,Fever, Katayama,Infection, Schistoma,Infections, Schistoma,Schistoma Infections,Schistosomiases
D013158	Splenic Diseases	Diseases involving the SPLEEN.	Disease, Splenic,Diseases, Splenic,Splenic Disease
D013163	Splenomegaly	Enlargement of the spleen.	Enlarged Spleen,Spleen, Enlarged