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25-Hydroxylation of vitamin D3 in liver microsomes and their smooth and rough subfractions. 1980

S Sulimovici, and M S Roginsky, and R F Pfeifer

UI MeSH Term Description Entries
D008297 Male Males
D008862 Microsomes, Liver Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough. Liver Microsomes,Liver Microsome,Microsome, Liver
D002458 Cell Fractionation Techniques to partition various components of the cell into SUBCELLULAR FRACTIONS. Cell Fractionations,Fractionation, Cell,Fractionations, Cell
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012279 Rickets Disorders caused by interruption of BONE MINERALIZATION manifesting as OSTEOMALACIA in adults and characteristic deformities in infancy and childhood due to disturbances in normal BONE FORMATION. The mineralization process may be interrupted by disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis, resulting from dietary deficiencies, or acquired, or inherited metabolic, or hormonal disturbances. Rachitis,Rachitides
D013250 Steroid Hydroxylases Cytochrome P-450 monooxygenases (MIXED FUNCTION OXYGENASES) that are important in steroid biosynthesis and metabolism. Steroid Hydroxylase,Steroid Monooxygenases,Hydroxylase, Steroid,Hydroxylases, Steroid,Monooxygenases, Steroid
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus
D053493 Cholestanetriol 26-Monooxygenase An NAPH-dependent cytochrome P450 enzyme that catalyzes the oxidation of the side chain of sterol intermediates such as the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. 5-beta-Cholestane-3-alpha,7-alpha,12-alpha-triol 27-Hydroxylase,C27-Steroid 26-Hydroxylase,Cytochrome P-450 Steroid 27-Hydroxylase,Cytochrome P-450 Sterol 26-Hydroxylase,Steroid 25-Hydroxylase,Steroid 27-Hydroxylase,Sterol 26-Hydroxylase,Sterol 27-Hydroxylase,Vitamin D3 25-Hydroxylase,C27 Steroid 26 Hydroxylase,Cholestanetriol 26 Monooxygenase,Cytochrome P 450 Steroid 27 Hydroxylase,Cytochrome P 450 Sterol 26 Hydroxylase,Steroid 25 Hydroxylase,Steroid 27 Hydroxylase,Sterol 26 Hydroxylase,Sterol 27 Hydroxylase,Vitamin D3 25 Hydroxylase

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