Biomaterial Database

[Effect of excess-protein rations on natural immunity indices]. 1980

A A Dzhumagaziev

Some parameters of natural immunity under conditions of the diets with optimal (18%) and excessive (28,33 and 43% by caloric value) protein content were studied in male Wistar rats. It was shown that a number of the parameters studied (the content of complement, lysozyme, beta-lysines, the normal antibody titer, phagocytic activity of leukocytes, skin bactericidal action) decreased with the elevation of the protein content in the diets 3 months after the beginning of the experiment. The bactericidal activity of the blood serum in all the animal groups remained unchanged. The animals kept on diets with 18 and 43% of protein for prolonged period of time were examined 6, 9 and 12 months after the beginning of the experiment. The parameters of natural immunity (except the content of complement and beta-lysines) in the group of animals receiving 43% of protein remained decreased as compared with the control.

UI	MeSH Term	Description	Entries
D007113	Immunity, Innate	The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from the presence of naturally occurring ANTI-INFECTIVE AGENTS, constitutional factors such as BODY TEMPERATURE and immediate acting immune cells such as NATURAL KILLER CELLS.	Immunity, Native,Immunity, Natural,Immunity, Non-Specific,Resistance, Natural,Innate Immune Response,Innate Immunity,Immune Response, Innate,Immune Responses, Innate,Immunity, Non Specific,Innate Immune Responses,Native Immunity,Natural Immunity,Natural Resistance,Non-Specific Immunity
D008297	Male		Males
D002149	Energy Intake	Total number of calories taken in daily whether ingested or by parenteral routes.	Caloric Intake,Calorie Intake,Intake, Calorie,Intake, Energy
D004044	Dietary Proteins	Proteins obtained from foods. They are the main source of the ESSENTIAL AMINO ACIDS.	Proteins, Dietary,Dietary Protein,Protein, Dietary
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus