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Serum group I pepsinogens (PG I) were determined by a radioimmunoassay method in blood drawn from premature and newborn infants, children of various ages, a control group of young healthy adults, and a group of women at delivery. Very low concentrations of PG I were found in blood of prematures and newborns, and there was no correlation between serum PG I in women at delivery and their newborn full-term infants. Serum PG I rose abruptly during the early months of life, but remained significantly reduced up to the age of 10 years. These findings are in agreement with those reports showing an increasing pepsin secretion during childhood, and thus indirectly lend support to the use of serum PG I as an estimate of gastric pepsin secretion.
H L Waldum, and
B K Straume, and
P G Burhol, and
L B Dahl
January 1981,
Scandinavian journal of gastroenterology,
H L Waldum, and
B K Straume, and
P G Burhol, and
L B Dahl
May 1981,
Clinical pediatrics,
H L Waldum, and
B K Straume, and
P G Burhol, and
L B Dahl
April 1974,
Gastroenterology,
H L Waldum, and
B K Straume, and
P G Burhol, and
L B Dahl
February 1984,
Gastroenterologie clinique et biologique,
H L Waldum, and
B K Straume, and
P G Burhol, and
L B Dahl
August 1986,
Journal of clinical gastroenterology,
H L Waldum, and
B K Straume, and
P G Burhol, and
L B Dahl
January 1980,
Scandinavian journal of gastroenterology,
H L Waldum, and
B K Straume, and
P G Burhol, and
L B Dahl
September 1984,
Postgraduate medical journal,
H L Waldum, and
B K Straume, and
P G Burhol, and
L B Dahl
January 1985,
Progress in clinical and biological research,
H L Waldum, and
B K Straume, and
P G Burhol, and
L B Dahl
December 1981,
Hepato-gastroenterology,
H L Waldum, and
B K Straume, and
P G Burhol, and
L B Dahl
April 1971,
Journal of immunology (Baltimore, Md. : 1950),
