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Five hundred and eighty homograft valves have been inserted into the aortic position as isolated valve replacements, and followed up for 7--14 years. After ten years 90% of frozen homografts, 80% of autografts and 70% of freeze-dried homografts were free of valve-related death. There was only one embolism reported giving an incidence of one embolism per 143,928 patient months. Degeneration occurred in 14% of the autografts, in 30% of the freeze dried and in 60% of the frozen homografts after ten years. Eighty per cent of the fresh homografts have been free of degeneration after seven years, and 54% of freeze-dried valves have been free of degeneration after 14 years. Long-term performance of homograft and autograft valves in the aortic positon is comparable to that of any prosthetic or bioprosthetic valve. In addition, they are non-thrombogenic and excellent in terms of patient survival.
E Bodnar, and
W H Wain, and
V Martelli, and
D N Ross
January 1989,
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D N Ross
July 1987,
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V Martelli, and
D N Ross
August 1972,
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D N Ross
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E Bodnar, and
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D N Ross
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D N Ross
April 1966,
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E Bodnar, and
W H Wain, and
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D N Ross
August 2000,
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E Bodnar, and
W H Wain, and
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D N Ross
November 1987,
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