Biomaterial Database

[Peptidase activity of Coccidioides immitis]. 1978

I M Klimova, and Iu A Goloseev, and A I Shelokhovich

Glycyl-L-leucinehydrolase consisting of three molecular units was extracted from C. immitis solid cultural medium. During fractionation in polyacrylamide gel of the enzyme-containing extract a 50-fold purification of the enzyme isoform with molecular weight 12,800 is achieved. The enzyme is heat-stable, active in the narrow pH range and hydrolizes peptide bonds containing glycine. Its activity is not inhibited by none of the protease inhibitors tested.

UI	MeSH Term	Description	Entries
D008970	Molecular Weight	The sum of the weight of all the atoms in a molecule.	Molecular Weights,Weight, Molecular,Weights, Molecular
D003045	Coccidioides	A mitosporic fungal genus which causes COCCIDIOIDOMYCOSIS.	Coccidioides immitis
D004150	Dipeptidases	EXOPEPTIDASES that specifically act on dipeptides. EC 3.4.13.
D005998	Glycine	A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.	Aminoacetic Acid,Glycine, Monopotassium Salt,Glycine Carbonate (1:1), Monosodium Salt,Glycine Carbonate (2:1), Monolithium Salt,Glycine Carbonate (2:1), Monopotassium Salt,Glycine Carbonate (2:1), Monosodium Salt,Glycine Hydrochloride,Glycine Hydrochloride (2:1),Glycine Phosphate,Glycine Phosphate (1:1),Glycine Sulfate (3:1),Glycine, Calcium Salt,Glycine, Calcium Salt (2:1),Glycine, Cobalt Salt,Glycine, Copper Salt,Glycine, Monoammonium Salt,Glycine, Monosodium Salt,Glycine, Sodium Hydrogen Carbonate,Acid, Aminoacetic,Calcium Salt Glycine,Cobalt Salt Glycine,Copper Salt Glycine,Hydrochloride, Glycine,Monoammonium Salt Glycine,Monopotassium Salt Glycine,Monosodium Salt Glycine,Phosphate, Glycine,Salt Glycine, Monoammonium,Salt Glycine, Monopotassium,Salt Glycine, Monosodium