-transparent.png){kind=logo}
Sixty unipolar depressed geriatric outpatients were subjects in a double-blind study of a new antidepressant, trazodone, versus imipramine and placebo. Over the four week study, patients in the two active medication groups improved significantly compared to placebo on both observer and self-ratings. Although imipramine and trazodone had similar therapeutic efficacy, trazodone was judged to have fewer side effects than imipramine, suggesting that trazodone may have particular clinical utility in the geriatric population which is especially vulnerable to cardiovascular and anticholinergic side effects.
Related Publications
R Gerner, and
W Estabrook, and
J Steuer, and
L Jarvik
December 1980,
Neuropharmacology,
R Gerner, and
W Estabrook, and
J Steuer, and
L Jarvik
March 1985,
The Journal of clinical psychiatry,
R Gerner, and
W Estabrook, and
J Steuer, and
L Jarvik
July 1965,
British medical journal,
R Gerner, and
W Estabrook, and
J Steuer, and
L Jarvik
March 1981,
Journal of clinical psychopharmacology,
R Gerner, and
W Estabrook, and
J Steuer, and
L Jarvik
February 1992,
The Journal of clinical psychiatry,
R Gerner, and
W Estabrook, and
J Steuer, and
L Jarvik
April 1984,
The Journal of clinical psychiatry,
R Gerner, and
W Estabrook, and
J Steuer, and
L Jarvik
August 1982,
Acta psychiatrica Scandinavica,
R Gerner, and
W Estabrook, and
J Steuer, and
L Jarvik
January 1987,
Psychopathology,
R Gerner, and
W Estabrook, and
J Steuer, and
L Jarvik
May 1983,
The American journal of psychiatry,
R Gerner, and
W Estabrook, and
J Steuer, and
L Jarvik
January 1983,
British journal of clinical pharmacology,
