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It was found that in patients with decreased serum folate concentration, urinary excretion of vitamin B12 was increased in a statistically highly significant way with both oral administration of 58 Co-labeled vitamin B12 and with a 57Co-labeled vitamin B12 intrinsic factor complex. This increased vitamin B12 excretion may account for some false normal Schilling test results. Furthermore, in folate deficiency, the intrinsic factor no longer seems required for vitamin B12 to pass the intestinal wall. It is also questionable whether vitamin B12 absorbed through the intestine under these circumstances could be properly metabolized. Besides statistical evidence, some clinical support for this theory is presented. These findings offer a possible clue for some literature reports that have lacked a satisfactory explanation.
E Van Royen, and
P Blockx, and
F Molter
April 1954,
Nutrition reviews,
E Van Royen, and
P Blockx, and
F Molter
May 2005,
The British journal of nutrition,
E Van Royen, and
P Blockx, and
F Molter
January 1963,
Revue des sciences medicales,
E Van Royen, and
P Blockx, and
F Molter
May 1955,
Clinical science,
E Van Royen, and
P Blockx, and
F Molter
May 1988,
Journal of the Medical Association of Thailand = Chotmaihet thangphaet,
E Van Royen, and
P Blockx, and
F Molter
August 1960,
Archives of biochemistry and biophysics,
E Van Royen, and
P Blockx, and
F Molter
April 1969,
British medical journal,
E Van Royen, and
P Blockx, and
F Molter
January 1997,
Annals of clinical and laboratory science,
E Van Royen, and
P Blockx, and
F Molter
January 1965,
Scandinavian journal of clinical and laboratory investigation,
