[Porphyrin excretion in normal (author's transl)]. 1980

M L Peña-Payero, and R Enriquez de Salamanca, and A Olmos, and F Romero, and M J Montes

Porphyrin excretion in normal subjects was studied by solvent extraction procedures and by thin-layer chromatography of their methyl-esters. The mean value of the urinary coproporphyrin fraction was significantly higher in males than in females. Taking age also into account this difference was not significant in subjects under 20 years of age. Within the same sex, age did not have any influence on this coproporphyrin fraction. Neither of these two factors, i.e. sex and age modified the mean values of uroporphyrin fraction. Males and females showed similar amounts of fecal copro and protoporphyrin fractions. The thin-layer chromatographic urinary pattern revealed a minor porcentual value of octo-carboxylic-porphyrin in males, due mainly to a lower amount of porphyrin in the 20-40 year, period, when males also showed a decreased value of heptacarboxylic-porphyrin. Neither sex nor age modified the fecal chromatographic porphyrin pattern. Di-carboxylic porphyrins were always predominant, but theri appraisal was very frequently interfered by the presence in feces of fluorescent substances with a Rf similar to tri-carboxylic-porphyrin but with a pheophytinlike spectra.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011166 Porphyrins A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin. Porphyrin
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D002855 Chromatography, Thin Layer Chromatography on thin layers of adsorbents rather than in columns. The adsorbent can be alumina, silica gel, silicates, charcoals, or cellulose. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Chromatography, Thin-Layer,Thin Layer Chromatography,Chromatographies, Thin Layer,Chromatographies, Thin-Layer,Thin Layer Chromatographies,Thin-Layer Chromatographies,Thin-Layer Chromatography
D003306 Coproporphyrins Porphyrins with four methyl and four propionic acid side chains attached to the pyrrole rings. Elevated levels of Coproporphyrin III in the urine and feces are major findings in patients with HEREDITARY COPROPORPHYRIA.
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

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