The reagin screen test: a new reagin card test for syphilis. 1980

R W March, and G E Stiles

A new card test for syphilis, the reagin screen test (RST), employs a stabilized cardiolipin--cholesterol-lecithin antigen stained with Sudan black. The sensitivity and specificity of the RST are essentially the same as those of the Venereal Disease Research Laboratory (VDRL) test. The RST is quick and is easy to perform since the specimen of serum does not have to be inactivated by heat or transferred from the tube into which blood was drawn. The results of the test are read macroscopically on a card. The RST antigen is ready to use at all times, and it is stable for at least two years.

UI MeSH Term Description Entries
D011935 Reagins Antibodies, especially IGE, that bind to tissue of the same species so that ANTIGENS induce HISTAMINE RELEASE and other vasoactive agents. HYPERSENSITIVITY is the clinical manifestation. Homocytotropic Antibodies,Reagin
D005189 False Positive Reactions Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed) False Positive Reaction,Positive Reaction, False,Positive Reactions, False,Reaction, False Positive,Reactions, False Positive
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000906 Antibodies Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).
D013588 Syphilis Serodiagnosis Serologic tests for syphilis. Kahn Test,Wassermann Reaction,Serodiagnosis, Syphilis,Reaction, Wassermann,Serodiagnoses, Syphilis,Syphilis Serodiagnoses,Test, Kahn

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