-transparent.png){kind=logo}
Midazolam, a new water-soluble benzodiazepine, was given intravenously in 5 and 10 mg doses to nine volunteers and plasma levels estimated at intervals for 24 hours. Recovery was also studied. the drug was easy and painless to inject and venous thrombosis was not found in this series. While there was a great individual variation in response to the drug this was not related to the weight of the subjects. Plasma levels declined rapidy and there was no 'second peak' effect. The half-life was between 60 and 90 min. Recovery was much more rapid than after comparable doses of diazepam.
Related Publications
J W Dundee, and
I O Samuel, and
W Toner, and
P J Howard
November 1982,
Anaesthesia and intensive care,
J W Dundee, and
I O Samuel, and
W Toner, and
P J Howard
July 1986,
Ugeskrift for laeger,
J W Dundee, and
I O Samuel, and
W Toner, and
P J Howard
May 1983,
Journal of the American Dental Association (1939),
J W Dundee, and
I O Samuel, and
W Toner, and
P J Howard
May 1979,
Anesthesiology,
J W Dundee, and
I O Samuel, and
W Toner, and
P J Howard
July 1985,
Anaesthesia,
J W Dundee, and
I O Samuel, and
W Toner, and
P J Howard
January 1985,
Pharmacotherapy,
J W Dundee, and
I O Samuel, and
W Toner, and
P J Howard
June 1985,
Minerva anestesiologica,
J W Dundee, and
I O Samuel, and
W Toner, and
P J Howard
January 1991,
Revista espanola de anestesiologia y reanimacion,
J W Dundee, and
I O Samuel, and
W Toner, and
P J Howard
April 1987,
AANA journal,
J W Dundee, and
I O Samuel, and
W Toner, and
P J Howard
September 1983,
Kokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan,
