[Plasma dopamine-beta-hydroxylase activity in pheochromocytoma (author's transl)]. 1980

J C Guilland, and B Caillard, and R Putelat, and C Klepping, and J Klepping, and M Malval

In 3 patients with proved pheochromocytoma, circulating catecholamine concentrations, vanillylmandelic acid and total free catecholamine urinary excretion, dopamine-beta-hydroxylase activities in plasma were measured the day before surgery, during the removal of the tumour and postoperatively. Following the removal of the pheochromocytoma, all these parameters declined with a different rate, possibly related to the half-life proper to each molecule. The results showing a decrease in plasma D beta H activities after the removal of the tumors are in good accordance with most authors. The mechanism and the meaning of catecholamines release from non-innervated tumor-cells remain to be elucidated. By considering these three cases, it does not seem that the evolution of D beta H activity after removal of the tumor is dependent upon the fact that the pheochromocytoma releases preferentially either epinephrine or nephinephrine.

UI MeSH Term Description Entries
D010673 Pheochromocytoma A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298) Pheochromocytoma, Extra-Adrenal,Extra-Adrenal Pheochromocytoma,Extra-Adrenal Pheochromocytomas,Pheochromocytoma, Extra Adrenal,Pheochromocytomas,Pheochromocytomas, Extra-Adrenal
D011184 Postoperative Period The period following a surgical operation. Period, Postoperative,Periods, Postoperative,Postoperative Periods
D002395 Catecholamines A general class of ortho-dihydroxyphenylalkylamines derived from TYROSINE. Catecholamine,Sympathin,Sympathins
D004299 Dopamine beta-Hydroxylase Dopamine beta-Monooxygenase,Dopamine beta Hydroxylase,Dopamine beta Monooxygenase,beta-Hydroxylase, Dopamine,beta-Monooxygenase, Dopamine
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000310 Adrenal Gland Neoplasms Tumors or cancer of the ADRENAL GLANDS. Adrenal Cancer,Adrenal Gland Cancer,Adrenal Neoplasm,Cancer of the Adrenal Gland,Neoplasms, Adrenal Gland,Adrenal Cancers,Adrenal Gland Cancers,Adrenal Gland Neoplasm,Adrenal Neoplasms,Cancer, Adrenal,Cancer, Adrenal Gland,Cancers, Adrenal,Cancers, Adrenal Gland,Neoplasm, Adrenal,Neoplasm, Adrenal Gland,Neoplasms, Adrenal
D014642 Vanilmandelic Acid A 3-O-methyl ether of 3,4-dihydroxymandelic acid. It is an end-stage metabolite of CATECHOLAMINES; EPINEPHRINE; and NOREPINEPHRINE. Methoxyhydroxymandelic Acid,4-Hydroxy-3-Methoxymandelic Acid,Vanillylmandelic Acid,4 Hydroxy 3 Methoxymandelic Acid,Acid, 4-Hydroxy-3-Methoxymandelic,Acid, Methoxyhydroxymandelic,Acid, Vanillylmandelic,Acid, Vanilmandelic

Related Publications

J C Guilland, and B Caillard, and R Putelat, and C Klepping, and J Klepping, and M Malval
July 1978, Nihon Jinzo Gakkai shi,
J C Guilland, and B Caillard, and R Putelat, and C Klepping, and J Klepping, and M Malval
November 1978, No to shinkei = Brain and nerve,
J C Guilland, and B Caillard, and R Putelat, and C Klepping, and J Klepping, and M Malval
June 1980, Nihon Jinzo Gakkai shi,
J C Guilland, and B Caillard, and R Putelat, and C Klepping, and J Klepping, and M Malval
October 1979, No to shinkei = Brain and nerve,
J C Guilland, and B Caillard, and R Putelat, and C Klepping, and J Klepping, and M Malval
August 1979, No to shinkei = Brain and nerve,
J C Guilland, and B Caillard, and R Putelat, and C Klepping, and J Klepping, and M Malval
August 1976, Clinica chimica acta; international journal of clinical chemistry,
J C Guilland, and B Caillard, and R Putelat, and C Klepping, and J Klepping, and M Malval
January 1978, Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis,
J C Guilland, and B Caillard, and R Putelat, and C Klepping, and J Klepping, and M Malval
May 1978, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine,
J C Guilland, and B Caillard, and R Putelat, and C Klepping, and J Klepping, and M Malval
November 1978, Nihon Naibunpi Gakkai zasshi,
J C Guilland, and B Caillard, and R Putelat, and C Klepping, and J Klepping, and M Malval
March 1976, Clinical endocrinology,
Copied contents to your clipboard!