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A newborn with aplasia cutis congenita is presented. The lesions involved the scalp and were symmetrical in trunk and lower extremities. Histologically there was a slightly epidermal flattening with disappearance of dermal papillae, and absence of elastic fibers and epidermal appendages. There was no evidence of either associated anomalies or familiar history of skin defects. The lesions, treated locally with antiseptics and antibiotics, healed with scarring in two-three months, and one year later were covered by a thin layer of skin devoid of hair in scalp.
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