The frequency of duodeno-pancreatic lesions in abdominal or thoraco-abdominal trauma hospitalized in the surgery clinic of the Emergency Hospital from Bucharest between 1960 and 1975 was of 0.57%. In the present study are stressed the important factors which influence the outcome of the interventions (age, the interval from the accident to hospitalization and that from hospitalization to surgery). The causes are described, that have generated abdominal trauma with duodeno-pancreatic lesions the intensity and the extension, the localization of the lesions, as well as the importance of the association with lesions of other organs. An analysis is made of the interventions that have been made, in which the type of duodeno-pancreatic lesion was taken into account, as well as the variety of the procedure applied, from the simple draining of the pancreatic lodge, and of the peritoneal cavity, to complex interventions including exeresis of the duodenum or of the pancreas. To conclude the authors show that duodeno-pancreatic lesions are of considerable severity and are one of the causes of high mortality. These lesions also represent a serious test for the surgeon when one has to make a decision on the technique to be performed during the intervention. These lesions are also very demanding from the viewpoint of the surgeon's technical capability.