Ion binding by small molecular weight substances (1,000-10,000 daltons) in urine. 1980

M J Nicar, and K Holt, and C Y Pak

The reliability of calculated activity products as an index of the urinary saturation of calcium oxalate was tested by comparing the solubility of calcium oxalate in various urine preparations. Urine samples were collected from six control subjects and nine patients with nephrolithiasis. From each sample four urine preparations were prepared: centrifugation at 1400 g. 0.22-mu filtration, ultrafiltration through a 10,000 daltons cutoff filter, and ultrafiltration through a 1000 daltons cutoff filter. Each preparation was incubated with an excess of calcium oxalate to steady-state, and the activity product of calcium oxalate was calculated for the ambient solution. Our findings suggest that most calcium and/or oxalate conplexes in urine that are not recognizable by available computational techniques for activity products probably reside in the fraction of 1000 to 10,000 daltons.

UI MeSH Term Description Entries
D007669 Kidney Calculi Stones in the KIDNEY, usually formed in the urine-collecting area of the kidney (KIDNEY PELVIS). Their sizes vary and most contains CALCIUM OXALATE. Kidney Stones,Renal Calculi,Nephrolith,Renal Calculus,Calculi, Kidney,Calculi, Renal,Calculus, Kidney,Calculus, Renal,Kidney Calculus,Kidney Stone,Stone, Kidney,Stones, Kidney
D002129 Calcium Oxalate The calcium salt of oxalic acid, occurring in the urine as crystals and in certain calculi. Calcium Oxalate (1:1),Calcium Oxalate Dihydrate,Calcium Oxalate Dihydrate (1:1),Calcium Oxalate Monohydrate,Calcium Oxalate Monohydrate (1:1),Calcium Oxalate Trihydrate,Dihydrate, Calcium Oxalate,Monohydrate, Calcium Oxalate,Oxalate, Calcium,Trihydrate, Calcium Oxalate
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012995 Solubility The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Solubilities

Related Publications

M J Nicar, and K Holt, and C Y Pak
October 1988, Analytical chemistry,
M J Nicar, and K Holt, and C Y Pak
June 1989, Cell structure and function,
M J Nicar, and K Holt, and C Y Pak
December 1986, European journal of clinical investigation,
M J Nicar, and K Holt, and C Y Pak
November 1971, Polski tygodnik lekarski (Warsaw, Poland : 1960),
M J Nicar, and K Holt, and C Y Pak
November 1979, Journal of the National Cancer Institute,
M J Nicar, and K Holt, and C Y Pak
October 1989, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica,
M J Nicar, and K Holt, and C Y Pak
February 2018, Journal of feline medicine and surgery,
Copied contents to your clipboard!