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Continuous tissue pH was measured using a minaturized glass electrode in 21 sick term and preterm infants. Tissue pH correlated well with arterial (r = 0.87) and capillary pH (r = 0.90) during the steady state. However, tpH was lower than arterial pH during hypoperfusion and state of shock. Improvement in tissue perfusion resulted in improvement in tpH and good correlation with arterial pH. The electrode was also sensitive to changes in carbon dioxide tension and adminitration of buffer. The good correlation with arterial pH and the feasibility of continuous recording of tissue pH makes it a useful instrument for monitoring the acid-base status of critically ill neonates.
R Bhat, and
D Vidyasagar, and
U O Asonye, and
C Papazafiratou
October 1985,
American journal of diseases of children (1960),
R Bhat, and
D Vidyasagar, and
U O Asonye, and
C Papazafiratou
July 2019,
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R Bhat, and
D Vidyasagar, and
U O Asonye, and
C Papazafiratou
January 1983,
Journal of medical engineering & technology,
R Bhat, and
D Vidyasagar, and
U O Asonye, and
C Papazafiratou
January 2012,
European journal of gastroenterology & hepatology,
R Bhat, and
D Vidyasagar, and
U O Asonye, and
C Papazafiratou
July 2005,
Current neurology and neuroscience reports,
R Bhat, and
D Vidyasagar, and
U O Asonye, and
C Papazafiratou
January 2005,
Neurocritical care,
R Bhat, and
D Vidyasagar, and
U O Asonye, and
C Papazafiratou
April 1980,
Journal of biomedical engineering,
R Bhat, and
D Vidyasagar, and
U O Asonye, and
C Papazafiratou
January 1992,
European journal of clinical pharmacology,
R Bhat, and
D Vidyasagar, and
U O Asonye, and
C Papazafiratou
January 2019,
Blood purification,
R Bhat, and
D Vidyasagar, and
U O Asonye, and
C Papazafiratou
June 1979,
British medical journal,
