Computer simulation of exercise hyperpnea. 1980

H Arita, and H Yamabayashi

An analog model which describes the behavior of gas exchange in the lung and of the respiratory control system has been developed to study the physiological mechanisms of exercise hyperpnea. The model consists of three major compartments (lung, brain and tissue) which are connected by circulation. The time delay to reach to the chemoreceptor site and the time constant of the chemoreceptor in response to changes in blood gases are included. Respiration is assumed to be controlled by both neurogenic and humoral factors which act independently and additively. The results showed that the model behavior in terms of steady-state and transient response to exercise and recovery from it was consistent with the experimental observations and suggested that the combination of humoral and neurogenic theory may explain the physiological mechanism of exercise hyperpnea.

UI MeSH Term Description Entries
D008433 Mathematics The deductive study of shape, quantity, and dependence. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Mathematic
D008954 Models, Biological Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment. Biological Model,Biological Models,Model, Biological,Models, Biologic,Biologic Model,Biologic Models,Model, Biologic
D012119 Respiration The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration ( Breathing
D003202 Computers, Analog Computers in which quantities are represented by physical variables; problem parameters are translated into equivalent mechanical or electrical circuits as an analog for the physical phenomenon being investigated. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Computers, Analogue,Analog Computer,Analog Computers,Analogue Computer,Analogue Computers,Computer, Analog,Computer, Analogue
D005082 Physical Exertion Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included. Physical Effort,Effort, Physical,Efforts, Physical,Exertion, Physical,Exertions, Physical,Physical Efforts,Physical Exertions

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