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At the basis of some ultrastructural differences in fetal, juvenile and adult rat triceps muscle capillaries as described in preliminary papers the permeability of these capillaries to horse radish peroxidase was investigated. Capillaries of fetal and juvenile rats up to the 3rd week after birth were impermeable to horse radish peroxidase (HRP) for 2 and 10 minutes after injection, which can be explained with the low pinocytotic activity and the more complex structure of the junctions. Capillaries of the triceps brachii muscle in adult rats aged 2 month and more show a low permeability to HRP 2 and 5 minutes and a high permeability 15 minutes after the injection of the tracer. In the capillary segment of the terminal bed the tracer was traversed especially by the means of vesicles and some transendothelial channels built by linked vesicles. The interendothelial junctions seemed to be tight. In the venular segment of th capillaries and in small postcapillary venules additional to the vesicular transport a high permeability of some junctions was stated. The significance of the different permeability of distinct segments of the terminal vascular bed to small macromolecules is discussed with respect to the theories of th physiologists and compared with the results of recent investigators.
K Welt, and
Y L Karaganov, and
K Schippel, and
G Schippel, and
W Scheller
January 1974,
Acta ophthalmologica,
K Welt, and
Y L Karaganov, and
K Schippel, and
G Schippel, and
W Scheller
January 1978,
Zeitschrift fur mikroskopisch-anatomische Forschung,
K Welt, and
Y L Karaganov, and
K Schippel, and
G Schippel, and
W Scheller
January 1974,
Acta ophthalmologica,
K Welt, and
Y L Karaganov, and
K Schippel, and
G Schippel, and
W Scheller
January 1971,
Zeitschrift fur Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948),
K Welt, and
Y L Karaganov, and
K Schippel, and
G Schippel, and
W Scheller
January 1984,
International review of cytology,
K Welt, and
Y L Karaganov, and
K Schippel, and
G Schippel, and
W Scheller
May 1995,
Nippon Ganka Gakkai zasshi,
K Welt, and
Y L Karaganov, and
K Schippel, and
G Schippel, and
W Scheller
January 1981,
Gegenbaurs morphologisches Jahrbuch,
K Welt, and
Y L Karaganov, and
K Schippel, and
G Schippel, and
W Scheller
November 1983,
Neuroscience,
K Welt, and
Y L Karaganov, and
K Schippel, and
G Schippel, and
W Scheller
February 1987,
The Histochemical journal,
K Welt, and
Y L Karaganov, and
K Schippel, and
G Schippel, and
W Scheller
October 1972,
Microvascular research,
