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A 39-year-old man, accused of driving a car under the influence of ethanol, claimed that the use of an oxitol-containing floor lacquer prior to the drive might have enhanced the concentration of ethanol. Since oxitol has a higher affinity to alcohol dehydrogenase than ethanol, interaction could not be excluded primarily. With the client's informed consent 104 g of ethanol was given orally in a chamber at exposure to 0 ppm and 316 ppm oxitol, respectively. No difference in the elimination rate of ethanol was found. After combined exposure to oxitol and ethanol a decrease of the neutrophilocytes and the thrombocytes was found, as well as an increase of the serum creatine kinase. After exposure solely to ethanol, there were no abnormal blood sample changes.
L M Pedersen, and
G D Nielsen, and
K H Cohr
November 1993,
Fundamental and applied toxicology : official journal of the Society of Toxicology,
L M Pedersen, and
G D Nielsen, and
K H Cohr
September 1999,
Journal of clinical forensic medicine,
L M Pedersen, and
G D Nielsen, and
K H Cohr
June 1982,
Scandinavian journal of work, environment & health,
L M Pedersen, and
G D Nielsen, and
K H Cohr
January 1982,
Drug and chemical toxicology,
L M Pedersen, and
G D Nielsen, and
K H Cohr
April 2002,
Toxicology and applied pharmacology,
L M Pedersen, and
G D Nielsen, and
K H Cohr
January 1966,
Pacific medicine and surgery,
L M Pedersen, and
G D Nielsen, and
K H Cohr
January 1961,
Archiv fur Toxikologie,
L M Pedersen, and
G D Nielsen, and
K H Cohr
June 1989,
British journal of industrial medicine,
L M Pedersen, and
G D Nielsen, and
K H Cohr
February 1997,
Environmental health perspectives,
L M Pedersen, and
G D Nielsen, and
K H Cohr
March 1980,
British medical journal,
