The policy of tuberculosis control in the Czechoslovak Socialist Republic has proved effective during the past 20 years under unfavourable epidemiological conditions. At present, however, it ceased to meet the requirements of the changing tuberculosis epidemiological situation. On the basis of data obtained from long-term follow-up of epidemiological indices and longitudinal epidemiological studies there was prepared a new system of compulsory reports on tuberculosis cases, supplemented with continuous supervision of persons registered for tuberculosis, and a proposal of centralized processing of the collected data. Starting January 1, 1981 a register of tuberculosis is planned in the Czech Socialist Republic which will utilize modern computer methods for ensuring the following objectives: 1. to establish data for operative and complex evaluation of epidemiological situation on tuberculosis in districts, regions and the total of Czech Socialist Republic, 2. to provide conditions for assessment of effectivity of tuberculosis control methods, to collect and evaluate data on basic economic aspects of tuberculosis control, 4. in a national project to elaborate and propose essential measures for the surveillance of tuberculosis applicable to existing conditions within the Czechoslovak Socialist Republic. The organization of the proposed tuberculosis register is described.