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Aluminium kinetics in patients with endstage renal failure and chronic intermittent haemodialysis have been studied. All patients revealed elevated predialytic serum aluminum levels. Because of a significant correlation between daily intake of aluminiumhydroxyd and serum aluminium levels it is concluded that the intestinal aluminium absorption plays an etiological role in the development of hyperaluminaemia. Plasma aluminium levels at the end of a regular dialysis procedure are significant lower compared to predialytic values. Similarly a significant decrease of aluminium concentration was observed in the plasma after passage through the dialyzer. This is due to the fact that the aluminium content of the dialysate used in our unit (0.1-0.3 mumol/l) is lower than the ultrafiltrable fraction of the plasma aluminium measured in vivo. Therefore a negative aluminium-balance during haemodialysis has to be assumed in our patients. Extreme aluminium-accummulation seems to be avoided and we therefore never experienced aluminium intoxication and dialysis dementia in our center. To assess a negative aluminium balance during haemodialysis, because of high protein binding of aluminium, a dialysate with an extreme low aluminium content has to be recommended.
H Graf, and
H K Stummvoll, and
J Kovarik, and
V Meisinger, and
A Wolf, and
W F Pinggera
January 1982,
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H Graf, and
H K Stummvoll, and
J Kovarik, and
V Meisinger, and
A Wolf, and
W F Pinggera
August 1976,
Rivista di patologia nervosa e mentale,
H Graf, and
H K Stummvoll, and
J Kovarik, and
V Meisinger, and
A Wolf, and
W F Pinggera
January 1980,
Deutsche medizinische Wochenschrift (1946),
H Graf, and
H K Stummvoll, and
J Kovarik, and
V Meisinger, and
A Wolf, and
W F Pinggera
January 1980,
L'Encephale,
H Graf, and
H K Stummvoll, and
J Kovarik, and
V Meisinger, and
A Wolf, and
W F Pinggera
January 1980,
Wiener klinische Wochenschrift,
H Graf, and
H K Stummvoll, and
J Kovarik, and
V Meisinger, and
A Wolf, and
W F Pinggera
February 1980,
Casopis lekaru ceskych,
H Graf, and
H K Stummvoll, and
J Kovarik, and
V Meisinger, and
A Wolf, and
W F Pinggera
March 1978,
Deutsche medizinische Wochenschrift (1946),
H Graf, and
H K Stummvoll, and
J Kovarik, and
V Meisinger, and
A Wolf, and
W F Pinggera
November 1979,
Wiener klinische Wochenschrift,
H Graf, and
H K Stummvoll, and
J Kovarik, and
V Meisinger, and
A Wolf, and
W F Pinggera
March 1980,
EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete,
H Graf, and
H K Stummvoll, and
J Kovarik, and
V Meisinger, and
A Wolf, and
W F Pinggera
January 1977,
Padiatrie und Padologie,
