Rapid radioimmunoassay for serum myoglobin. 1980

M Reichlin, and D P Copley, and F J Klocke

A rapid radioimmunoassay for serum myoglobin concentration has been developed, capitalizing on a technique for rapid separation of antibody-bound antigen from free antigen using Sepharose-bound sheep anti-rabbit gamma-globulin. Total time required for the assay is 2.75 h, making it suitable for clinical approaches employing myoglobin for rapid identification of patients in the active phase of myocardial injury.

UI MeSH Term Description Entries
D009203 Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). Cardiovascular Stroke,Heart Attack,Myocardial Infarct,Cardiovascular Strokes,Heart Attacks,Infarct, Myocardial,Infarction, Myocardial,Infarctions, Myocardial,Infarcts, Myocardial,Myocardial Infarctions,Myocardial Infarcts,Stroke, Cardiovascular,Strokes, Cardiovascular
D009211 Myoglobin A conjugated protein which is the oxygen-transporting pigment of muscle. It is made up of one globin polypeptide chain and one heme group.
D011863 Radioimmunoassay Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation. Radioimmunoassays
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

M Reichlin, and D P Copley, and F J Klocke
January 1978, Annals of clinical and laboratory science,
M Reichlin, and D P Copley, and F J Klocke
January 1980, Horumon to rinsho. Clinical endocrinology,
M Reichlin, and D P Copley, and F J Klocke
March 1983, Horumon to rinsho. Clinical endocrinology,
M Reichlin, and D P Copley, and F J Klocke
January 1981, Journal of neurology, neurosurgery, and psychiatry,
M Reichlin, and D P Copley, and F J Klocke
January 1980, Journal of immunoassay,
M Reichlin, and D P Copley, and F J Klocke
June 1981, Canadian Medical Association journal,
M Reichlin, and D P Copley, and F J Klocke
August 1977, Steroids,
M Reichlin, and D P Copley, and F J Klocke
January 1977, Clinical chemistry,
M Reichlin, and D P Copley, and F J Klocke
November 1980, Horumon to rinsho. Clinical endocrinology,
M Reichlin, and D P Copley, and F J Klocke
January 1977, Arthritis and rheumatism,
Copied contents to your clipboard!