Early scar plasticity as a cause of scar contracture. 1980

R Fujimori

Little is known about the cause of scar contracture. The contractile capability of myofibroblasts in the early scar provides a partial explanation; however, clinical and experimental findings indicate that the early scar possesses plasticity, and that its size and shape can be altered by mechanical forces. Even if a scar possesses no contractile capability itself, scar contracture may develop if: (1) the affected joint (skin) is kept in flexion (relaxation); (2) the scar is over a contracted wound; or (3) compression is applied to the early scar. Many instances of scar contracture may therefore be attributable not to active motility but to the passive response of scar tissue to mechanical forces.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008297 Male Males
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002921 Cicatrix The fibrous tissue that replaces normal tissue during the process of WOUND HEALING. Scars,Cicatrization,Scar,Scarring
D003286 Contracture Prolonged shortening of the muscle or other soft tissue around a joint, preventing movement of the joint. Contractures
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D013314 Stress, Mechanical A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area. Mechanical Stress,Mechanical Stresses,Stresses, Mechanical

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