BIOMAT Database Logo BIOMAT Database Logo

Differences in the repair of DNA strand breaks induced by 9-hydroxy-benzo(a)pyrene and trans-7,8-dihydro-7,8-dihydroxy-benzo(a)pyrene in cultured human fibroblasts. 1978

M Nordenskjöld, and S Söderhäll, and P Moldéus, and B Jernström

UI MeSH Term Description Entries
D008297 Male Males
D008748 Methylcholanthrene A carcinogen that is often used in experimental cancer studies. 20-Methylcholanthrene,3-Methylcholanthrene,20 Methylcholanthrene,3 Methylcholanthrene
D008862 Microsomes, Liver Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough. Liver Microsomes,Liver Microsome,Microsome, Liver
D002478 Cells, Cultured Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others. Cultured Cells,Cell, Cultured,Cultured Cell
D004260 DNA Repair The removal of DNA LESIONS and/or restoration of intact DNA strands without BASE PAIR MISMATCHES, intrastrand or interstrand crosslinks, or discontinuities in the DNA sugar-phosphate backbones. DNA Damage Response
D004277 DNA, Single-Stranded A single chain of deoxyribonucleotides that occurs in some bacteria and viruses. It usually exists as a covalently closed circle. Single-Stranded DNA,DNA, Single Stranded,Single Stranded DNA
D005347 Fibroblasts Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules. Fibroblast
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001580 Benzopyrenes A class of chemicals that contain an anthracene ring with a naphthalene ring attached to it. Benzpyrene

Related Publications

M Nordenskjöld, and S Söderhäll, and P Moldéus, and B Jernström
3-Hydroxy-trans-7,8-dihydro-7,8-dihydroxy-benzo(a)pyrene, a metabolite of 3-hydroxybenzo(a)pyrene.
January 1986, Advances in experimental medicine and biology,
M Nordenskjöld, and S Söderhäll, and P Moldéus, and B Jernström
A comparative investigation of DNA adducts, DNA strand breaks and gene mutations induced by benzo[a]pyrene and (+/-)-anti-benzo[a]pyrene-7,8-diol 9,10-oxide in cultured human cells.
April 1997, Mutation research,
M Nordenskjöld, and S Söderhäll, and P Moldéus, and B Jernström
Oxidation of benzo(a)pyrene and 7,8-dihydro-7,8-dihydroxy benzo(a)pyrene by horseradish peroxidase-H2O2 intermediate: fluorometric study.
June 1984, Cancer biochemistry biophysics,
M Nordenskjöld, and S Söderhäll, and P Moldéus, and B Jernström
Induction and repair of DNA strand breaks in cultured human fibroblasts exposed to various phenols and dihydrodiols of benzo[a]pyrene.
August 1982, Chemico-biological interactions,
M Nordenskjöld, and S Söderhäll, and P Moldéus, and B Jernström
Differences in the DNA adducts formed in cultured rabbit and rat dermal fibroblasts by benzo(a)pyrene and (-)benzo(a)pyrene-7,8-diol.
December 1988, Cancer research,
M Nordenskjöld, and S Söderhäll, and P Moldéus, and B Jernström
Metabolism of (+/-)-trans-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in mouse liver microsomes and the effect of 2(3)-tert-butyl-4-hydroxy-anisole.
January 1982, Carcinogenesis,
M Nordenskjöld, and S Söderhäll, and P Moldéus, and B Jernström
Stereospecificity of metabolism of benzo[a]pyrene (BP) to (+/-)trans-7,8-dihydroxy-7,8-dihydro-BP by rat liver nuclear enzymes.
January 1979, Biochemical pharmacology,
M Nordenskjöld, and S Söderhäll, and P Moldéus, and B Jernström
Arachidonic acid-dependent metabolism of (+/-) trans-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene (BP-7,8 DIOL) to 7,10/8,9 tetrols.
October 1979, FEBS letters,
M Nordenskjöld, and S Söderhäll, and P Moldéus, and B Jernström
Hydroperoxide-dependent oxygenation of trans-7,8-dihydroxy-7,8-dihydro benzo[a]pyrene by ram seminal vesicle microsomes. Source of the oxygen.
September 1980, Biochemical and biophysical research communications,
M Nordenskjöld, and S Söderhäll, and P Moldéus, and B Jernström
Comparison of benzo(a)pyrene and (-)-trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene metabolism in human blood monocytes and lymphocytes.
August 1979, Cancer research,
Copied contents to your clipboard!