Monoclonal immunoglobulins demonstrable in cerebrospinal fluid by use of cellulose acetate electrophoresis. 1980

H J van der Helm, and E A Hische, and H K van Walbeek

UI MeSH Term Description Entries
D007136 Immunoglobulins Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses. Globulins, Immune,Immune Globulin,Immune Globulins,Immunoglobulin,Globulin, Immune
D009103 Multiple Sclerosis An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903) MS (Multiple Sclerosis),Multiple Sclerosis, Acute Fulminating,Sclerosis, Disseminated,Disseminated Sclerosis,Sclerosis, Multiple
D004588 Electrophoresis, Cellulose Acetate Electrophoresis in which cellulose acetate is the diffusion medium. Cellulose Acetate Electrophoreses,Cellulose Acetate Electrophoresis,Electrophoreses, Cellulose Acetate
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

H J van der Helm, and E A Hische, and H K van Walbeek
September 1977, Arquivos de neuro-psiquiatria,
H J van der Helm, and E A Hische, and H K van Walbeek
June 1967, Das Deutsche Gesundheitswesen,
H J van der Helm, and E A Hische, and H K van Walbeek
December 1984, Psychiatrie, Neurologie, und medizinische Psychologie,
H J van der Helm, and E A Hische, and H K van Walbeek
January 1979, Laboratornoe delo,
H J van der Helm, and E A Hische, and H K van Walbeek
October 1974, Rinsho byori. The Japanese journal of clinical pathology,
H J van der Helm, and E A Hische, and H K van Walbeek
October 1974, Rinsho byori. The Japanese journal of clinical pathology,
H J van der Helm, and E A Hische, and H K van Walbeek
July 1972, Monatsschrift fur Kinderheilkunde,
H J van der Helm, and E A Hische, and H K van Walbeek
October 1966, Clinical chemistry,
H J van der Helm, and E A Hische, and H K van Walbeek
January 1979, Voprosy meditsinskoi khimii,
H J van der Helm, and E A Hische, and H K van Walbeek
January 1983, Methods in enzymology,
Copied contents to your clipboard!