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The response of 13 pigs to total pancreatectomy was compared with the response of 9 animals to sham operation. Approximately half of each group had free access to food while the remainder received oral water only. Completeness of pancreatectomy was confirmed at autopsy, and the disappearance of insulin and the rise in blood glucose to 14-19 mmol/l. Immunoreactive glucagon (IRG) increased in fed pancreatectomized pigs from the 3rd day postoperatively to a level of 350-400% of basal values by the 8th day. There was no rise in starved pancreatectomized animals, or in either group of sham-operated animals. The rises in glucose, free fatty acids, triglycerides and ketones were similar in the two groups of pigs.
W A van Hoorn, and
A I Vinik, and
R van Hoorn-Hickman, and
J Terblanche
November 1976,
Metabolism: clinical and experimental,
W A van Hoorn, and
A I Vinik, and
R van Hoorn-Hickman, and
J Terblanche
July 1984,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
W A van Hoorn, and
A I Vinik, and
R van Hoorn-Hickman, and
J Terblanche
August 1968,
The Journal of laboratory and clinical medicine,
W A van Hoorn, and
A I Vinik, and
R van Hoorn-Hickman, and
J Terblanche
October 1978,
Diabetes,
W A van Hoorn, and
A I Vinik, and
R van Hoorn-Hickman, and
J Terblanche
December 1978,
European journal of biochemistry,
W A van Hoorn, and
A I Vinik, and
R van Hoorn-Hickman, and
J Terblanche
January 1957,
Surgical forum,
W A van Hoorn, and
A I Vinik, and
R van Hoorn-Hickman, and
J Terblanche
February 1980,
Endocrinologia japonica,
W A van Hoorn, and
A I Vinik, and
R van Hoorn-Hickman, and
J Terblanche
June 1974,
Diabetes,
W A van Hoorn, and
A I Vinik, and
R van Hoorn-Hickman, and
J Terblanche
April 1973,
The Journal of clinical endocrinology and metabolism,
W A van Hoorn, and
A I Vinik, and
R van Hoorn-Hickman, and
J Terblanche
July 1963,
The Journal of clinical investigation,
