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The Ca2+-dependent phosphorylation of a number of proteins in the cytosol of the rat or guinea pig cerebral cortex was profoundly stimulated by phosphatidylserine; calmodulin, on the other hand, had only a minimal effect. The Ca2+-dependent phosphorylation of different proteins from the total particulate fraction of the same tissue, in comparison, was specifically stimulated by either phosphatidylserine or calmodulin. The present findings, in line with the phospholipid-sensitive Ca2+-dependent protein kinase recently recognized, suggest an involvement of phospholipid in regulating Ca2+-dependent phosphorylation of endogenous substrate proteins. This new system presumably functions independent or in a complementary manner with the calmodulin-sensitive Ca2+-dependent protein phosphorylation system previously reported by others.
R W Wrenn, and
N Katoh, and
B C Wise, and
J F Kuo
August 1985,
Biochemical and biophysical research communications,
R W Wrenn, and
N Katoh, and
B C Wise, and
J F Kuo
April 2004,
Neurochemical research,
R W Wrenn, and
N Katoh, and
B C Wise, and
J F Kuo
December 1990,
Molecular and cellular endocrinology,
R W Wrenn, and
N Katoh, and
B C Wise, and
J F Kuo
August 1996,
Brain research. Molecular brain research,
R W Wrenn, and
N Katoh, and
B C Wise, and
J F Kuo
June 1982,
Diabetes,
R W Wrenn, and
N Katoh, and
B C Wise, and
J F Kuo
July 1985,
Neuroscience letters,
R W Wrenn, and
N Katoh, and
B C Wise, and
J F Kuo
June 1984,
Proceedings of the National Academy of Sciences of the United States of America,
R W Wrenn, and
N Katoh, and
B C Wise, and
J F Kuo
March 1983,
Journal of neurochemistry,
R W Wrenn, and
N Katoh, and
B C Wise, and
J F Kuo
July 1990,
Proceedings of the National Academy of Sciences of the United States of America,
R W Wrenn, and
N Katoh, and
B C Wise, and
J F Kuo
November 1983,
The Journal of biological chemistry,
