Effect of bombesin and ceruletide on prolactin, growth hormone, luteinizing hormone, and parathyroid hormone release in normal human males. 1980

A E Pontiroli, and M Alberetto, and L Restelli, and A Facchinetti

To investigate the possible role of gastrointestinal peptides on PRL, GH, LH, and parathyroid hormone release, bombesin (10 ng/kg . min for 60 min) and ceruletide (2 ng/kg . min for 60 min) infusions were performed in eight normal subjects. Bombesin elicited PRL release in six of eight subjects. The other hormones were not affected by either peptide. The possible effect of bombesin and ceruletide on PRL, GH, LH, and parathyroid hormone release in response to specific stimuli deserve further investigation.

UI MeSH Term Description Entries
D007700 Kinetics The rate dynamics in chemical or physical systems.
D007986 Luteinizing Hormone A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity. ICSH (Interstitial Cell Stimulating Hormone),Interstitial Cell-Stimulating Hormone,LH (Luteinizing Hormone),Lutropin,Luteoziman,Luteozyman,Hormone, Interstitial Cell-Stimulating,Hormone, Luteinizing,Interstitial Cell Stimulating Hormone
D008297 Male Males
D010281 Parathyroid Hormone A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates. Natpara,PTH (1-84),PTH(1-34),Parathormone,Parathyrin,Parathyroid Hormone (1-34),Parathyroid Hormone (1-84),Parathyroid Hormone Peptide (1-34),Hormone, Parathyroid
D010455 Peptides Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are considered to be larger versions of peptides that can form into complex structures such as ENZYMES and RECEPTORS. Peptide,Polypeptide,Polypeptides
D011388 Prolactin A lactogenic hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). It is a polypeptide of approximately 23 kD. Besides its major action on lactation, in some species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation and osmoregulation. Prolactin receptors are present in the mammary gland, hypothalamus, liver, ovary, testis, and prostate. Lactogenic Hormone, Pituitary,Mammotropic Hormone, Pituitary,Mammotropin,PRL (Prolactin),Hormone, Pituitary Lactogenic,Hormone, Pituitary Mammotropic,Pituitary Lactogenic Hormone,Pituitary Mammotropic Hormone
D001839 Bombesin A tetradecapeptide originally obtained from the skins of toads Bombina bombina and B. variegata. It is also an endogenous neurotransmitter in many animals including mammals. Bombesin affects vascular and other smooth muscle, gastric secretion, and renal circulation and function. Bombesin 14,Bombesin Dihydrochloride,Dihydrochloride, Bombesin
D002108 Ceruletide A specific decapeptide obtained from the skin of Hila caerulea, an Australian amphibian. Caerulein is similar in action and composition to CHOLECYSTOKININ. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle. It is used in paralytic ileus and as diagnostic aid in pancreatic malfunction. Caerulein,Cerulein,Ceruletid,FI-6934,Takus,FI 6934,FI6934
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

A E Pontiroli, and M Alberetto, and L Restelli, and A Facchinetti
November 1973, The Journal of clinical endocrinology and metabolism,
A E Pontiroli, and M Alberetto, and L Restelli, and A Facchinetti
April 1976, Fertility and sterility,
A E Pontiroli, and M Alberetto, and L Restelli, and A Facchinetti
February 1982, Endocrinology,
A E Pontiroli, and M Alberetto, and L Restelli, and A Facchinetti
April 1992, Drug and alcohol dependence,
A E Pontiroli, and M Alberetto, and L Restelli, and A Facchinetti
November 1975, The Journal of clinical endocrinology and metabolism,
A E Pontiroli, and M Alberetto, and L Restelli, and A Facchinetti
November 1993, The Journal of clinical endocrinology and metabolism,
A E Pontiroli, and M Alberetto, and L Restelli, and A Facchinetti
August 1980, The Journal of clinical endocrinology and metabolism,
A E Pontiroli, and M Alberetto, and L Restelli, and A Facchinetti
October 1979, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
A E Pontiroli, and M Alberetto, and L Restelli, and A Facchinetti
September 1991, Human reproduction (Oxford, England),
A E Pontiroli, and M Alberetto, and L Restelli, and A Facchinetti
August 1978, Endocrinology,
Copied contents to your clipboard!