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In order to examine tumorigenic effects of fusarenon-X, a trichothecene compound produced by Fusarium nivale, feeding experiments on 151 male Donryu rats were carried out. Daily dose of 105 micrograms (7 ppm in the diet) or 50 micrograms (3.5 ppm)/animal of fusarenon-X was given for 1 or 2 years. Although the animals of the experimental groups showed lower body weight than controls and were more liable to be afflicted by pulmonary infections, tumor incidences were as low as that of the control group. However, several unusual tumors as follows were observed only in the experimental groups: 1 adenocarcinoma of the stomach, 2 papillary carcinomas of the urinary bladder, 1 adrenocortical adenoma, and 1 leukemia.
M Saito, and
T Horiuchi, and
K Ohtsubo, and
Y Hatanaka, and
Y Ueno
June 1980,
The Japanese journal of experimental medicine,
M Saito, and
T Horiuchi, and
K Ohtsubo, and
Y Hatanaka, and
Y Ueno
August 1970,
Japanese journal of medical science & biology,
M Saito, and
T Horiuchi, and
K Ohtsubo, and
Y Hatanaka, and
Y Ueno
February 1970,
Chemical & pharmaceutical bulletin,
M Saito, and
T Horiuchi, and
K Ohtsubo, and
Y Hatanaka, and
Y Ueno
December 1987,
Toxicology and applied pharmacology,
M Saito, and
T Horiuchi, and
K Ohtsubo, and
Y Hatanaka, and
Y Ueno
August 1979,
Toxicology and applied pharmacology,
M Saito, and
T Horiuchi, and
K Ohtsubo, and
Y Hatanaka, and
Y Ueno
March 1981,
Toxicology and applied pharmacology,
M Saito, and
T Horiuchi, and
K Ohtsubo, and
Y Hatanaka, and
Y Ueno
December 1972,
Biochimica et biophysica acta,
M Saito, and
T Horiuchi, and
K Ohtsubo, and
Y Hatanaka, and
Y Ueno
March 1982,
Journal of pharmacobio-dynamics,
M Saito, and
T Horiuchi, and
K Ohtsubo, and
Y Hatanaka, and
Y Ueno
December 1987,
Toxicology and applied pharmacology,
M Saito, and
T Horiuchi, and
K Ohtsubo, and
Y Hatanaka, and
Y Ueno
April 1982,
Immunology,
