Biomaterial Database

Hematological, splenic and adrenal changes associated with natural and experimental infections of Trypanosoma lemmi in the Norwegian lemming, Lemmus lemmus (L.). 1978

R Wiger

Both natural and experimental Trypanosoma lemmi infections in Norwegian lemmings caused slight anemias and hypoglycemia. Leucocyte counts remained the same. Adrenal and splenic hypertrophy were associated with natural infections whereas only splenic hypertrophy was present in the experimental infection. Grahamella sp. infections were also associated with adrenal and splenic hypertrophy in wild lemmings. It is suggested that blood parasites which are associated with anemia, hypoglycemia and adrenal hypertrophy might also interfere with both male and female reproduction, and should be considered in the interpretation of the population regulation of small rodents.

UI	MeSH Term	Description	Entries
D006984	Hypertrophy	General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).	Hypertrophies
D009664	Norway	A country located in northern Europe, bordering the North Sea and the Atlantic Ocean, west of Sweden. The capital is Oslo.	Kingdom of Norway
D006400	Hematocrit	The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.	Erythrocyte Volume, Packed,Packed Red-Cell Volume,Erythrocyte Volumes, Packed,Hematocrits,Packed Erythrocyte Volume,Packed Erythrocyte Volumes,Packed Red Cell Volume,Packed Red-Cell Volumes,Red-Cell Volume, Packed,Red-Cell Volumes, Packed,Volume, Packed Erythrocyte,Volume, Packed Red-Cell,Volumes, Packed Erythrocyte,Volumes, Packed Red-Cell
D000311	Adrenal Glands	A pair of glands located at the cranial pole of each of the two KIDNEYS. Each adrenal gland is composed of two distinct endocrine tissues with separate embryonic origins, the ADRENAL CORTEX producing STEROIDS and the ADRENAL MEDULLA producing NEUROTRANSMITTERS.	Adrenal Gland,Gland, Adrenal,Glands, Adrenal
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012376	Rodent Diseases	Diseases of rodents of the order RODENTIA. This term includes diseases of Sciuridae (squirrels), Geomyidae (gophers), Heteromyidae (pouched mice), Castoridae (beavers), Cricetidae (rats and mice), Muridae (Old World rats and mice), Erethizontidae (porcupines), and Caviidae (guinea pigs).	Disease, Rodent,Diseases, Rodent,Rodent Disease
D012377	Rodentia	A mammalian order which consists of 29 families and many genera.	Beavers,Capybaras,Castor Beaver,Dipodidae,Hydrochaeris,Jerboas,Rodents,Beaver,Capybara,Hydrochaeri,Jerboa,Rodent,Rodentias
D013154	Spleen	An encapsulated lymphatic organ through which venous blood filters.
D014345	Trypanosoma	A genus of flagellate protozoans found in the BLOOD and LYMPH of vertebrates and invertebrates, both hosts being required to complete the life cycle.	Nannomonas,Trypanosomes,Nannomona,Trypanosome
D014352	Trypanosomiasis	Infection with protozoa of the genus TRYPANOSOMA.	Trypanosomiases