-transparent.png){kind=logo}
The leucocyte ascorbic acid content is widely used as a measure of tissue ascorbic acid status. Standard methods of analysis, however, isolate both leucocytes and platelets (buffy layer), with consequent overestimation, since platelet ascorbic acid is attributed to the leucocytes. Fourteen healthy individuals on ascorbic acid supplements and 11 patients on mega dose ascorbic acid therapy were studied. A significant correlation was demonstrated between the 'leucocyte' ascorbic acid content and the platelet: leucocyte ratio (r = 0.70, P < 0.001). It is suggested that changes in the relative distribution of platelets and leucocytes in the blood will result in an apparent change in the 'leucocyte' ascorbic acid content regardless of any actual change in the ascorbic acid content of the cells.
R M Evans, and
L Currie, and
A Campbell
January 1972,
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition,
R M Evans, and
L Currie, and
A Campbell
January 1972,
British medical journal,
R M Evans, and
L Currie, and
A Campbell
February 1976,
Age and ageing,
R M Evans, and
L Currie, and
A Campbell
September 1976,
British poultry science,
R M Evans, and
L Currie, and
A Campbell
January 1976,
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition,
R M Evans, and
L Currie, and
A Campbell
May 1979,
The British journal of nutrition,
R M Evans, and
L Currie, and
A Campbell
October 1979,
Fertility and sterility,
R M Evans, and
L Currie, and
A Campbell
May 1966,
British medical journal,
R M Evans, and
L Currie, and
A Campbell
January 1945,
Annals of biochemistry and experimental medicine,
R M Evans, and
L Currie, and
A Campbell
January 1976,
Journal of clinical pathology,
