-transparent.png){kind=logo}
An 18-month-old boy presented with general hypotonia, decreased muscle strength, retarded motor development and stunted growth. The excretion of dicarboxylic acids was enhanced. EMG was normal. A muscle biopsy revealed a lipid storage myopathy. Oral daily supplementation with 2 g D, L-carnitine resulted in: (1) an increase of the growth velocity; (2) increased muscle strength, and (3) a decrease in the lipid fraction of the fibre volume. The carnitine content of the muscle biopsied prior to treatment appeared to be normal.
Related Publications
R C Sengers, and
J A Bakkeren, and
J M Trijbels, and
A M Stadhouders, and
G J Egberink, and
H J ter Laak, and
H J Jaspar
February 1985,
Neuropediatrics,
R C Sengers, and
J A Bakkeren, and
J M Trijbels, and
A M Stadhouders, and
G J Egberink, and
H J ter Laak, and
H J Jaspar
October 1982,
Neurology,
R C Sengers, and
J A Bakkeren, and
J M Trijbels, and
A M Stadhouders, and
G J Egberink, and
H J ter Laak, and
H J Jaspar
June 1981,
British medical journal (Clinical research ed.),
R C Sengers, and
J A Bakkeren, and
J M Trijbels, and
A M Stadhouders, and
G J Egberink, and
H J ter Laak, and
H J Jaspar
March 1975,
Journal of the neurological sciences,
R C Sengers, and
J A Bakkeren, and
J M Trijbels, and
A M Stadhouders, and
G J Egberink, and
H J ter Laak, and
H J Jaspar
February 1982,
Acta neurologica,
R C Sengers, and
J A Bakkeren, and
J M Trijbels, and
A M Stadhouders, and
G J Egberink, and
H J ter Laak, and
H J Jaspar
December 1979,
Journal of medical genetics,
R C Sengers, and
J A Bakkeren, and
J M Trijbels, and
A M Stadhouders, and
G J Egberink, and
H J ter Laak, and
H J Jaspar
July 1993,
Muscle & nerve,
R C Sengers, and
J A Bakkeren, and
J M Trijbels, and
A M Stadhouders, and
G J Egberink, and
H J ter Laak, and
H J Jaspar
February 1977,
Journal of neurology, neurosurgery, and psychiatry,
R C Sengers, and
J A Bakkeren, and
J M Trijbels, and
A M Stadhouders, and
G J Egberink, and
H J ter Laak, and
H J Jaspar
February 2010,
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology,
R C Sengers, and
J A Bakkeren, and
J M Trijbels, and
A M Stadhouders, and
G J Egberink, and
H J ter Laak, and
H J Jaspar
January 1977,
European neurology,
