Biomaterial Database

Abnormal diastolic blood pressure and heart rate reactions to tilting in diabetes mellitus. 1980

G Sundkvist, and B Lilja, and L O Almér

The orthostatic reaction to tilting was studied in 46 diabetics without symptoms of autonomic neuropathy and in 31 age-matched healthy control subjects. After tilting, the diastolic blood pressure rose in the control subject but was unchanged or tended to fall in the diabetics, except in those of short duration without retinopathy. After tilting, the control subjects showed an immediate increase in heart rate with the highest value at 8.4 +/- 1.0 s (mean +/- SEM), followed by a transient decrease with lowest value at 21.2 +/- 0.9 s. The acceleration and brake index measured the changes in heart rate. The brake index was lower in diabetics of short duration with retinopathy (6.9 +/- 1.6) than in those without (14.4 +/- 2.3, P < 0.01) as well as matched control subjects (18.7 +/- 2.5, P 0.01). In the diabetics of long duration no differences were shown between those with or without retinopathy but the accleration (10.3 +/- 1.6 vs 19.9 /!- 2.3, P < 0.05) and the brake index (5.3 +/- 1.4 vs 19.9 +/- 2.3, P < 0.01) were lower in those with vagal neuropathy.

UI	MeSH Term	Description	Entries
D007024	Hypotension, Orthostatic	A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.	Hypotension, Postural,Orthostatic Hypotension,Postural Hypotension
D008297	Male		Males
D008451	Maximal Voluntary Ventilation	Measure of the maximum amount of air that can be breathed in and blown out over a sustained interval such as 15 or 20 seconds. Common abbreviations are MVV and MBC.	Maximal Breathing Capacity,MVV (Ventilation),Breathing Capacities, Maximal,Breathing Capacity, Maximal,Capacities, Maximal Breathing,Capacity, Maximal Breathing,Maximal Breathing Capacities,Maximal Voluntary Ventilations,Ventilation, Maximal Voluntary,Ventilations, Maximal Voluntary,Voluntary Ventilation, Maximal,Voluntary Ventilations, Maximal
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011187	Posture	The position or physical attitude of the body.	Postures
D001794	Blood Pressure	PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.	Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D003920	Diabetes Mellitus	A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
D005260	Female		Females
D006339	Heart Rate	The number of times the HEART VENTRICLES contract per unit of time, usually per minute.	Cardiac Rate,Chronotropism, Cardiac,Heart Rate Control,Heartbeat,Pulse Rate,Cardiac Chronotropy,Cardiac Chronotropism,Cardiac Rates,Chronotropy, Cardiac,Control, Heart Rate,Heart Rates,Heartbeats,Pulse Rates,Rate Control, Heart,Rate, Cardiac,Rate, Heart,Rate, Pulse
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man