-transparent.png){kind=logo}
A study of the alterations in the intracellular electrolytes in the left failing heart due to induced mitral insufficiency was made in dogs. The extracellular space increased significantly. There was no significant change in the plasma Na+ and Ca++. However, there was a significant decrease in the plasma K+. The ratio of wet weight to dry weight increased during mitral insufficiency, although not significantly. There were no significant changes in the tissue Na+, K+ and Ca++. However, there were significant decreases in the intracellular Na+ and Ca++, and tendency for an increase in the intracellular K+ during mitral insufficiency. These results suggest that the decrease in the myocardial contractility in chronic heart failure due to mitral insufficiency might be due to a decrease in the intracellular Ca++ and associated changes in Na+ and K+ as a result of increased sarcolemmal ATPase.
J C Khatter, and
P K Singal, and
B Bharadwaj, and
K Prasad
September 1958,
Medicina panamericana,
J C Khatter, and
P K Singal, and
B Bharadwaj, and
K Prasad
March 1985,
The Canadian journal of cardiology,
J C Khatter, and
P K Singal, and
B Bharadwaj, and
K Prasad
January 1966,
Studii si cercetari de medicina interna,
J C Khatter, and
P K Singal, and
B Bharadwaj, and
K Prasad
January 1986,
Acta medica Scandinavica. Supplementum,
J C Khatter, and
P K Singal, and
B Bharadwaj, and
K Prasad
February 1994,
Revue medicale de la Suisse romande,
J C Khatter, and
P K Singal, and
B Bharadwaj, and
K Prasad
January 1966,
Studii si cercetari de medicina interna,
J C Khatter, and
P K Singal, and
B Bharadwaj, and
K Prasad
July 1965,
Terapevticheskii arkhiv,
J C Khatter, and
P K Singal, and
B Bharadwaj, and
K Prasad
December 1978,
Schweizerische medizinische Wochenschrift,
J C Khatter, and
P K Singal, and
B Bharadwaj, and
K Prasad
December 1963,
International abstracts of surgery,
J C Khatter, and
P K Singal, and
B Bharadwaj, and
K Prasad
August 1958,
Revista medica de Chile,
