The effect of Hydron burn wound dressing on burned rat and rabbit ear wound healing. 1980

D P Dressler, and W K Barbee, and R Sprenger

The effect of Hydron burn wound dressing was evaluated using a standard Walker burned rat model (N = 156) and a rabbit ear wound model (N = 34). In both studies Hydron was administered only once in one group and changed twice weekly in another. Animals were predesignated as controls and for pathologic examination. Gross observations, including photographic documentation, and the pathologic analyses revealed no gross purulence or sepsis. No deaths occurred in the rabbit study. Of the 156 animals in the rat study only two died; a culture of the wounds revealed no sepsis. Statistical analyses revealed that in the rat study the once only application was significantly better at 7 days postburn than the twice weekly treatment and control groups. No significant differences among the treatment and control groups used in the rabbit study were revealed. The application of Hydron burn wound dressing did not adversely affect the wound healing.

UI MeSH Term Description Entries
D008297 Male Males
D011102 Polyhydroxyethyl Methacrylate A biocompatible, hydrophilic, inert gel that is permeable to tissue fluids. It is used as an embedding medium for microscopy, as a coating for implants and prostheses, for contact lenses, as microspheres in adsorption research, etc. Glycol Methacrylate Gel,Hydroxymethacrylate Gel,PHEMA,Poly-Hema,Polyglycol Methacrylate,Gel, Glycol Methacrylate,Gel, Hydroxymethacrylate,Methacrylate Gel, Glycol,Methacrylate, Polyglycol,Methacrylate, Polyhydroxyethyl,Poly Hema
D011109 Polymethacrylic Acids Poly-2-methylpropenoic acids. Used in the manufacture of methacrylate resins and plastics in the form of pellets and granules, as absorbent for biological materials and as filters; also as biological membranes and as hydrogens. Synonyms: methylacrylate polymer; poly(methylacrylate); acrylic acid methyl ester polymer. Methacrylic Acid Polymers,Acid Polymers, Methacrylic,Acids, Polymethacrylic,Polymers, Methacrylic Acid
D011817 Rabbits A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes. Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D002056 Burns Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like. Burn
D004423 Ear The hearing and equilibrium system of the body. It consists of three parts: the EXTERNAL EAR, the MIDDLE EAR, and the INNER EAR. Sound waves are transmitted through this organ where vibration is transduced to nerve signals that pass through the ACOUSTIC NERVE to the CENTRAL NERVOUS SYSTEM. The inner ear also contains the vestibular organ that maintains equilibrium by transducing signals to the VESTIBULAR NERVE. Vestibulocochlear System,Vestibulocochlear Apparatus,Apparatus, Vestibulocochlear,Ears,System, Vestibulocochlear
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001458 Bandages Material used for wrapping or binding any part of the body. Dressings,Bandage,Dressing
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D014945 Wound Healing Restoration of integrity to traumatized tissue. Healing, Wound,Healings, Wound,Wound Healings

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