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A generator of 81mKr was designed and tested. The parent nuclide 81Rb was produced by the 70 MeV proton induced reactions on a Rb2SO4 target. 81mKr was bubbled out with oxygen gas from the 81Rb solution, and collected in a reservoir for lung ventilation studies. The generator was continuously operated at the high flow rate up to 10 1/min. The generator efficiency was 86%. The collection rates in the reservoir were examined under several flow rates. The pure 81mKr isomer was observed wih a NaI (T1) detector at the reservoir.
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