Biomaterial Database

[Comparative study of five different methods for measuring urinary porphyrins (author's transl)]. 1978

G Usuelli, and S Piccinini, and E Alessi, and M Basagni

The AA. have compared five different methods for measuring urinary porphyrins (Bio-Rad porphyrins, Porphyrin-T Sibar, Reinkingh-Van Kampen, Schwartz and coll., Fischer-Ham). Based on the results obtained, for total porphyrins the best method appeared to be the Porphyrin-T Sibar test, while for the separate evaluation of uro- and coproporphyrins the most suitable method proved to be the one proposed by Reinkingh-Van Kampen. The investigations has also allowed the AA. to conclude that spectrophotometric reading can replace the fluorimetric one, without affecting the accuracy of results.

UI	MeSH Term	Description	Entries
D008722	Methods	A series of steps taken in order to conduct research.	Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D011164	Porphyrias	A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.	Porphyria,Porphyrin Disorder,Disorder, Porphyrin,Disorders, Porphyrin,Porphyrin Disorders
D011166	Porphyrins	A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin.	Porphyrin
D003306	Coproporphyrins	Porphyrins with four methyl and four propionic acid side chains attached to the pyrrole rings. Elevated levels of Coproporphyrin III in the urine and feces are major findings in patients with HEREDITARY COPROPORPHYRIA.
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013053	Spectrophotometry	The art or process of comparing photometrically the relative intensities of the light in different parts of the spectrum.
D014578	Uroporphyrins	Porphyrins with four acetic acid and four propionic acid side chains attached to the pyrrole rings.