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A patient is reported who presented with severe arterial hypertension and pronounced hypokalemic metabolic alkalosis along with suppression of 17-hydroxicorticoids, plasma renin activity and urinary aldosterone excretion, in relation to topical application of 9-alpha-fluoroprednisolone, 300 mg weekly. The clinical picture changed after discontinuation of the steroid preparation. Whenever topical steroids are prescribed for extensive chronic skin the development of systemic side-effects must be watched. Depending on the type of steroid employed, Cushing's syndrome or a hypermineralcorticism state may appear. The differential diagnosis of a hypermineralcorticism syndrome without aldosteronism should include the possible topical application of fluorated steroids.
F Vasconez, and
R Pérez-Garcia, and
E Olivas, and
J E Bolívar, and
F Valderrábano
November 1984,
Clinical nephrology,
F Vasconez, and
R Pérez-Garcia, and
E Olivas, and
J E Bolívar, and
F Valderrábano
September 1983,
Revista clinica espanola,
F Vasconez, and
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F Vasconez, and
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F Vasconez, and
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F Valderrábano
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F Vasconez, and
R Pérez-Garcia, and
E Olivas, and
J E Bolívar, and
F Valderrábano
December 1983,
Clinical nephrology,
F Vasconez, and
R Pérez-Garcia, and
E Olivas, and
J E Bolívar, and
F Valderrábano
December 1984,
Clinical nephrology,
F Vasconez, and
R Pérez-Garcia, and
E Olivas, and
J E Bolívar, and
F Valderrábano
January 1985,
Giornale di clinica medica,
