Biomaterial Database

[Contraception by progestational agents administered in sequential form (author's transl)]. 1980

J Barrat, and F Durand Chèné

On the basis of a study involving 2338 months of treatment with progestational agents administered in sequential form from the 10th to the 25th day of the cycle, in women during the premenopausal period or suffering from benign or malignant breast pathology, the authors evaluated the contraceptive efficacy of this treatment. This efficacy was found to be good (Pearl index: 1 to 1,6%) with norsteroid progestational agents and inadequate with hydroxyprogesterone derivatives. It would thus appear possible to ensure coincidence of therapeutic action and contraception when norsteroids are used after the age of 40 (lower fertility) and/or when other methods are contraindicated.

UI	MeSH Term	Description	Entries
D008593	Menopause	The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.	Change of Life, Female
D008598	Menstruation	The periodic shedding of the ENDOMETRIUM and associated menstrual bleeding in the MENSTRUAL CYCLE of humans and primates. Menstruation is due to the decline in circulating PROGESTERONE, and occurs at the late LUTEAL PHASE when LUTEOLYSIS of the CORPUS LUTEUM takes place.
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009654	Norsteroids	Steroids which have undergone contraction in ring size or reduction in side chains.
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D003276	Contraceptives, Oral	Compounds, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. The hormones are generally estrogen or progesterone or both.	Low-Dose Oral Contraceptive,Oral Contraceptive,Oral Contraceptives,Oral Contraceptives, Low-Dose,Oral Contraceptives, Phasic,Contraceptive, Low-Dose Oral,Contraceptive, Oral,Contraceptives, Low-Dose Oral,Contraceptives, Phasic Oral,Low Dose Oral Contraceptive,Low-Dose Oral Contraceptives,Oral Contraceptive, Low-Dose,Oral Contraceptives, Low Dose,Phasic Oral Contraceptives
D003279	Contraceptives, Oral, Sequential	Drugs administered orally and sequentially for contraceptive purposes.	Contraceptive Agents, Female Sequential,Contraceptive Agents, Oral, Sequential,Oral Contraceptive Agents, Sequential,Oral Contraceptives, Sequential,Sequential Oral Contraceptive Agents,Contraceptives, Sequential Oral,Sequential Oral Contraceptives
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults