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Alcoholism has been shown to predispose to cerebrovascular thrombosis in normotensive males under the age of 50. To elucidate this phenomenon platelet aggregation and fibrinolytic activity were studied in 29 alcoholic males under 50 years of age who showed no evidence of acute cerebrovascular disease. Age matched healthy nonalcoholic volunteers made up the control population. Platelet aggregation did not differ significantly (P greater than 0.05) in the two groups. Fibrinolytic activity was significantly reduced in the alcoholics as compared to the controls (P = 0.005). The data suggest that the alcoholics have an increased thrombotic tendency. This may cause alcoholics to be at a greater risk of suffering stroke at an early age.
K Lee, and
J D Nielsen, and
I Zeeberg, and
J Gormsen
January 1977,
Acta neurologica Scandinavica,
K Lee, and
J D Nielsen, and
I Zeeberg, and
J Gormsen
March 1994,
Clinical physiology (Oxford, England),
K Lee, and
J D Nielsen, and
I Zeeberg, and
J Gormsen
June 1980,
Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova,
K Lee, and
J D Nielsen, and
I Zeeberg, and
J Gormsen
February 1984,
Sheng zhi yu bi yun = Reproduction and contraception,
K Lee, and
J D Nielsen, and
I Zeeberg, and
J Gormsen
October 1992,
The American journal of cardiology,
K Lee, and
J D Nielsen, and
I Zeeberg, and
J Gormsen
April 1986,
Thrombosis and haemostasis,
K Lee, and
J D Nielsen, and
I Zeeberg, and
J Gormsen
February 1978,
Journal of neurology, neurosurgery, and psychiatry,
K Lee, and
J D Nielsen, and
I Zeeberg, and
J Gormsen
January 1973,
Annales de cardiologie et d'angeiologie,
K Lee, and
J D Nielsen, and
I Zeeberg, and
J Gormsen
April 1979,
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K Lee, and
J D Nielsen, and
I Zeeberg, and
J Gormsen
December 1987,
Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence,
