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Xenon Xe 133 clearance was used to select the most distal amputation level that would allow sufficient blood flow for healing. Capillary blood flow was first measured at the most distal potential amputation level, then at successive proximal levels until an amputation site was found that had a capillary skin blood flow rate greater than or equal to 2.6 mL/min/100 g of tissue. Xenon Xe 133 in saline (100 to 500 mCi) was injected intracutaneously at each level, and flow rates were determined using a gamma camera interfaced with a computer system programmed for the Ketty-Schmidt formula modified for capillary blood flow. There were 45 cases, including one toes, six transmetatarsal, five Syme's, 25 below-knee, four knee disarticulation, three above-knee, and one hip disarticulation amputation. All amputations in patients with flow rates exceeding 2.4 mL/min/100 g of tissue healed, with two exceptions.
W S Moore, and
R E Henry, and
J M Malone, and
M J Daly, and
D Patton, and
S J Childers
November 1973,
Archives of surgery (Chicago, Ill. : 1960),
W S Moore, and
R E Henry, and
J M Malone, and
M J Daly, and
D Patton, and
S J Childers
January 1967,
Scandinavian journal of clinical and laboratory investigation. Supplementum,
W S Moore, and
R E Henry, and
J M Malone, and
M J Daly, and
D Patton, and
S J Childers
July 1975,
Archives of surgery (Chicago, Ill. : 1960),
W S Moore, and
R E Henry, and
J M Malone, and
M J Daly, and
D Patton, and
S J Childers
January 1968,
Scandinavian journal of plastic and reconstructive surgery,
W S Moore, and
R E Henry, and
J M Malone, and
M J Daly, and
D Patton, and
S J Childers
January 1972,
Polish medical journal,
W S Moore, and
R E Henry, and
J M Malone, and
M J Daly, and
D Patton, and
S J Childers
January 1974,
Surgical forum,
W S Moore, and
R E Henry, and
J M Malone, and
M J Daly, and
D Patton, and
S J Childers
January 1976,
Acta chirurgica Academiae Scientiarum Hungaricae,
W S Moore, and
R E Henry, and
J M Malone, and
M J Daly, and
D Patton, and
S J Childers
January 1975,
VASA. Zeitschrift fur Gefasskrankheiten,
W S Moore, and
R E Henry, and
J M Malone, and
M J Daly, and
D Patton, and
S J Childers
January 1977,
Radiobiologia, radiotherapia,
W S Moore, and
R E Henry, and
J M Malone, and
M J Daly, and
D Patton, and
S J Childers
October 1973,
The Journal of investigative dermatology,
