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Drebrin A expression was induced in non-neuronal L cells via transfection with a vector containing the cDNA of rat drebrin A. Following treatment with colcemid (5 micrograms/ml) and cytochalasin D (0.5 micrograms/ml), most L cells collapsed into round cells, while drebrin expressing cells were resistant to the treatment, keeping their cell shapes. Simultaneously, actin filaments and microtubules were disrupted in both cell lines. By quantitative analysis, in the presence of cytochalasin D, the extent of cell spreading and cell attachment in drebrin expressing cells was significantly higher than that in control cells. These results suggest that drebrin A modulates cell-substratum adhesion.
K Ikeda, and
T Shirao, and
M Toda, and
H Asada, and
S Toya, and
K Uyemura
May 2016,
Arteriosclerosis, thrombosis, and vascular biology,
K Ikeda, and
T Shirao, and
M Toda, and
H Asada, and
S Toya, and
K Uyemura
January 2012,
PloS one,
K Ikeda, and
T Shirao, and
M Toda, and
H Asada, and
S Toya, and
K Uyemura
May 2010,
Journal of molecular biology,
K Ikeda, and
T Shirao, and
M Toda, and
H Asada, and
S Toya, and
K Uyemura
June 2014,
Histology and histopathology,
K Ikeda, and
T Shirao, and
M Toda, and
H Asada, and
S Toya, and
K Uyemura
September 2013,
The Journal of biological chemistry,
K Ikeda, and
T Shirao, and
M Toda, and
H Asada, and
S Toya, and
K Uyemura
August 2006,
Experimental cell research,
K Ikeda, and
T Shirao, and
M Toda, and
H Asada, and
S Toya, and
K Uyemura
September 2019,
Nature communications,
K Ikeda, and
T Shirao, and
M Toda, and
H Asada, and
S Toya, and
K Uyemura
January 1996,
Journal of neuroscience research,
K Ikeda, and
T Shirao, and
M Toda, and
H Asada, and
S Toya, and
K Uyemura
April 2010,
Histology and histopathology,
K Ikeda, and
T Shirao, and
M Toda, and
H Asada, and
S Toya, and
K Uyemura
April 2010,
Journal of cell science,
